Gastrin-Releasing Peptide, human

Basic Information

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CAS Number

93755-85-2

Molecular Formula

C130H204N38O31S2

Molecular Weight

2859.38 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.46±0.1 g/cm3 (20 ºC 760 Torr),

SMILES

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CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CNC=N1)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CNC=N4)NC(=O)C(CC(=O)N)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C5CCCN5C(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C(C)O)NC(=O)CNC(=O)CNC(=O)CNC(=O)C(C)NC(=O)C7CCCN7C(=O)C(CC(C)C)NC(=O)C8CCCN8C(=O)C(C(C)C)N

InChI

1S/C130H204N38O31S2/c1-65(2)47-86(115(185)152-82(108(134)178)38-45-200-17)156-116(186)89(52-77-56-137-63-146-77)150-101(176)62-145-123(193)104(69(9)10)163-110(180)72(14)148-114(184)88(51-76-55-140-81-28-20-19-27-80(76)81)157-117(187)90(53-78-57-138-64-147-78)158-118(188)91(54-97(132)172)151-100(175)61-144-111(181)83(30-23-41-139-130(135)136)154-121(191)95-32-25-43-167(95)128(198)93(50-75-34-36-79(171)37-35-75)160-113(183)85(39-46-201-18)153-112(182)84(29-21-22-40-131)155-125(195)107(74(16)170)165-119(189)87(48-66(3)4)159-124(194)105(70(11)12)164-126(196)106(73(15)169)162-102(177)60-142-98(173)58-141-99(174)59-143-109(179)71(13)149-120(190)94-31-24-42-166(94)127(197)92(49-67(5)6)161-122(192)96-33-26-44-168(96)129(199)103(133)68(7)8/h19-20,27-28,34-37,55-57,63-74,82-96,103-107,140,169-171H,21-26,29-33,38-54,58-62,131,133H2,1-18H3,(H2,132,172)(H2,134,178)(H,137,146)(H,138,147)(H,141,174)(H,142,173)(H,143,179)(H,144,181)(H,145,193)(H,148,184)(H,149,190)(H,150,176)(H,151,175)(H,152,185)(H,153,182)(H,154,191)(H,155,195)(H,156,186)(H,157,187)(H,158,188)(H,159,194)(H,160,183)(H,161,192)(H,162,177)(H,163,180)(H,164,196)(H,165,189)(H4,135,136,139)/t71-,72-,73+,74+,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,103-,104-,105-,106-,107-/m0/s1

InChIKey

PUBCCFNQJQKCNC-XKNFJVFFSA-N

LogP

-8.635129999999961

Topological Polar Surface Area

1064.1900000000003 Å²

Hydrogen Bond Donor/Acceptor

41 / 69

Complexity

6470

Synonyms & References

English

Gastrin-releasingpeptide (human) (9CI)
Gastrin Releasing Peptide human
GASTRIN RELEASING PEPTIDE
Gastrin Releasing Peptide humanGastrin Releasing Pepti
GRP (human)
Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2
VPLPAGGGTVLTKMYPRGNHWAVGHLM-NH2
Human gastrin releasing peptide (1-27)
Human gastrin-releasing peptide
L-Valyl-L-prolyl-L-leucyl-L-prolyl-L-alanylglycylglycylglycyl-L-threonyl-L-valyl-L-leucyl-L-threonyl-L-lysyl-L-methionyl-L-tyrosyl-L-prolyl-L-arginylglycyl-L-asparaginyl-L-histidyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-L-methioninamide (ACI)
L
Gastrin-releasing peptide (human) (9CI)
Gastrin-releasing peptide (pig), 1-L-valine-3-L-leucine-4-L-proline-5-L-alanine-12-L-threonine- (ZCI)
93: PN: US20060293232 PAGE: 15 unclaimed sequence
[1-27]-Human gastrin-releasing peptide
Gastrin-Releasing Peptide, human
Valylprolylleucylprolylalanylglycylglycylglycylthreonylvalylleucylthreonyllysylmethionyltyrosylprolylarginylglycylasparaginylhistidyltryptophylalanylvalylglycylhistidylleucylmethioninamide
DA-73877
GASTRIN RELEASING PEPTIDE, HUMAN
93755-85-2
DTXSID00631217

MDL Number

MFCD00133362

FAQ

What is Gastrin-Releasing Peptide (CAS: 93755-85-2)?

Gastrin-Releasing Peptide (GRP) is a bioactive peptide with a molecular weight of approximately 7.2 kDa. It plays a crucial role in stimulating the release of gastrin from G cells in the antrum of the stomach. GRP is a 27-amino acid peptide with the sequence Ac-IGFSLGDFLRKLLPEDRQSLYKQKKK-NH2.

What are the main uses of Gastrin-Releasing Peptide (CAS: 93755-85-2)?

Gastrin-Releasing Peptide (GRP) is primarily used in research, particularly in studies related to gastrointestinal physiology and pathology. It also has potential applications in the development of treatments for stomach disorders and other conditions involving the gastrointestinal tract.

Is Gastrin-Releasing Peptide (CAS: 93755-85-2) safe?

Gastrin-Releasing Peptide (GRP) is generally considered safe under controlled laboratory conditions. However, it is important to follow all safety precautions and use appropriate protective measures, such as gloves and lab coats, when handling this substance.

How should Gastrin-Releasing Peptide (CAS: 93755-85-2) be stored?

Gastrin-Releasing Peptide (GRP) should be stored at -20°C to -80°C in the freezer to maintain its stability. It should be protected from light and stored in airtight containers to prevent degradation.