5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one

Basic Information

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CAS Number

93609-84-8

Molecular Formula

C18H15NO3

Molecular Weight

293.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

174-176 ºC

Boiling Point

569.179℃ at 760 mmHg

Density

1.230

SMILES

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CC(=O)C1=C2C=CC(=O)NC2=C(C=C1)OCC3=CC=CC=C3

InChI

InChI=1S/C18H15NO3/c1-12(20)14-7-9-16(18-15(14)8-10-17(21)19-18)22-11-13-5-3-2-4-6-13/h2-9H,10-11H2,1H3

InChIKey

JLOSXVISUUPMPY-UHFFFAOYSA-N

LogP

1.7986

Topological Polar Surface Area

55.73 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

453

Synonyms & References

English

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one
5-Acetyl-8-(phenylmethoxy)-2-quinolinone
5-Acetyl-8-(benzyloxy)-1,2-dihydroquinolin-2-one
5-acetyl-8-(Benzyloxy)-2(1H)-Quinolinone
5-acetyl-8-phenylmethoxy-1H-quinolin-2-one
5-acetyl-8-benzyloxycarbostyril
acetyl-5 benzyloxy-8 carbostyrile
acetylbenzyloxydihydroquinolinone
5-Acetyl-8-(benzyloxy)carbostyril
5-Acetyl-8-benzyloxy-2(1H)-quinolinone
8-(Benzyloxy)-5-(1-oxoethyl)-1H-quinolin-2-one
5-acetyl-8-benzyloxy-1H-quinolin-2-one
2(1H)-Quinolinone, 5-acetyl-8-(phenylmethoxy)-
MVYPGJMOODJFAZ-UHFFFAOYSA-N
5896AC
OR61366
5-acetyl-8-benzyloxyquinolin-2(1h)-one
5-Acetyl-8-benzyloxyquinoline-2(1H)-one
5-Acetyl-8-(phenylmethoxy)-2
5-Acetyl-8-(phenylmethoxy)-2(1H)-quinolinone (ACI)
5-Acetyl-8-benzyloxy-1H-quinolin-2-one
5-acetyl-8-(benzyloxy)-1,2-dihydroquinolin-2-one
CS-0155086
SY061038
DTXSID80538654
8-(phenylmethoxy)-5-acetyl-(1H)-quinolin-2-one
AKOS015991346
5-acetyl-8-benzyloxy-(1H)-quinolin-2-one
5-acetyl-8-(benzyloxy)-1H-quinolin-2-one
5-ACETYL-8-(BENZYLOXY)-2(1H)-QUINOLINONE
93609-84-8

MDL Number

MFCD19381743

Customs Code

2933790090

FAQ

What are the physical and chemical properties of 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8)?

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8) is a crystalline solid with a molecular weight of approximately 358.33 g/mol. It has a high solubility in organic solvents such as dichloromethane and acetone but is poorly soluble in water. This compound exhibits moderate reactivity towards nucleophiles and electrophiles, making it useful in various chemical transformations.

How is 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8) typically synthesized?

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one is commonly synthesized via the condensation of acetophenone with 8-hydroxyquinoline followed by benzylation. The reaction typically employs triphenylphosphine as a base, and the product can be isolated with an overall yield of about 70-80%. The process is selective and efficient.

What industries use 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8)?

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8) is primarily used in the pharmaceutical and chemical industries for the development of novel drugs and materials. It is also explored for its potential in polymer synthesis and as a sensing agent in analytical chemistry.

What precautions should be taken when handling 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8)?

When handling 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. In case of a spill, neutralize with an appropriate chemical agent and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling instructions.