5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one(CAS: 93609-84-8)

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8) is a crystalline solid with a molecular weight of approximately 358.33 g/mol. It has a high solubility in organic solvents such as dichloromethane and acetone but is poorly soluble in water. This compound exhibits moderate reactivity towards nucleophiles and electrophiles, making it useful in various chemical transformations.

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one is commonly synthesized via the condensation of acetophenone with 8-hydroxyquinoline followed by benzylation. The reaction typically employs triphenylphosphine as a base, and the product can be isolated with an overall yield of about 70-80%. The process is selective and efficient.

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8) is primarily used in the pharmaceutical and chemical industries for the development of novel drugs and materials. It is also explored for its potential in polymer synthesis and as a sensing agent in analytical chemistry.

When handling 5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one (CAS: 93609-84-8), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. In case of a spill, neutralize with an appropriate chemical agent and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling instructions.