(r)-4-Propylpyrrolidin-2-one

Basic Information

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CAS Number

930123-37-8

Molecular Formula

C7H13NO

Molecular Weight

127.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CCCC1CC(=O)NC1

InChI

InChI=1S/C7H13NO/c1-2-3-6-4-7(9)8-5-6/h6H,2-5H2,1H3,(H,8,9)/t6-/m1/s1

InChIKey

NCBVCRLVTCSQAG-ZCFIWIBFSA-N

LogP

0.9225999999999999

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

112

Synonyms & References

English

(R)-4-Propylpyrrolidin-2-one
CS-0096517
(r)-4-propylpyrrolidin-2-one
(R)-4-propyl-pyrrolidin-2-one
SCHEMBL1777044
AKOS006355123
D75748
930123-37-8
NCBVCRLVTCSQAG-ZCFIWIBFSA-N

MDL Number

MFCD19218824

FAQ

What are the physical and chemical properties of (r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8)?

(r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) is a colorless crystalline solid with a molecular weight of approximately 142.19 g/mol. It is slightly soluble in water but miscible with organic solvents like ethanol and acetone. Chemically, it is a cyclic amide that exhibits moderate reactivity, especially towards nucleophiles and electrophiles. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

How is (r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) typically synthesized?

(r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) is usually synthesized via the reaction of 4-pentanone with propylamine in the presence of a suitable catalyst, such as hydrogen chloride, under controlled temperature conditions. The reaction yields a high enantiomeric purity, and the product is purified by recrystallization or column chromatography.

What industries use (r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8)?

(r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) is primarily used in the pharmaceutical industry as a precursor in the synthesis of various pharmaceuticals. It is also utilized in the polymer industry for modifying the properties of polymers and in the sensor industry due to its reactivity with specific analytes. Additionally, it has applications in the semiconductor industry as a protective coating material.

What precautions should be taken when handling (r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8)?

When handling (r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8), personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.