(r)-4-Propylpyrrolidin-2-one(CAS: 930123-37-8)

(r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) is a colorless crystalline solid with a molecular weight of approximately 142.19 g/mol. It is slightly soluble in water but miscible with organic solvents like ethanol and acetone. Chemically, it is a cyclic amide that exhibits moderate reactivity, especially towards nucleophiles and electrophiles. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

(r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) is usually synthesized via the reaction of 4-pentanone with propylamine in the presence of a suitable catalyst, such as hydrogen chloride, under controlled temperature conditions. The reaction yields a high enantiomeric purity, and the product is purified by recrystallization or column chromatography.

(r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8) is primarily used in the pharmaceutical industry as a precursor in the synthesis of various pharmaceuticals. It is also utilized in the polymer industry for modifying the properties of polymers and in the sensor industry due to its reactivity with specific analytes. Additionally, it has applications in the semiconductor industry as a protective coating material.

When handling (r)-4-Propylpyrrolidin-2-one (CAS: 930123-37-8), personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.