5-Bromo-2-chloro-3-iodopyridine

Basic Information

View in Editor

CAS Number

928653-73-0

Molecular Formula

C5H2BrClIN

Molecular Weight

318.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1=C(C=NC(=C1I)Cl)Br

InChI

InChI=1S/C5H2BrClIN/c6-3-1-4(8)5(7)9-2-3/h1-2H

InChIKey

ZAGGSGCNNVVSII-UHFFFAOYSA-N

LogP

3.1021

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

103

Safety Information

View Safety Information

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

5-Bromo-2-chloro-3-iodopyridine
5-Bromo-2-chloro-3-iodo-pyridine
Pyridine,5-bromo-2-chloro-3-iodo-
ZAGGSGCNNVVSII-UHFFFAOYSA-N
2-chloro -5-bromo-3-iodopyridine
AB48194
FCH1324244
OR345455
AX8026180
ST2418632
V9212
5-Bromo-2-chloro-3-iodo-pyridine, AldrichCPR
5-Bromo-2-chloro-3-iodopyridine (ACI)
DTXSID30640054
DS-17131
CS-W005426
SY110056
SCHEMBL487372
EN300-316805
DB-029747
928653-73-0
AKOS015834456
MFCD08688585

MDL Number

MFCD08688585

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Bromo-2-chloro-3-iodopyridine (CAS: 928653-73-0)?

5-Bromo-2-chloro-3-iodopyridine is a crystalline solid with a molecular weight of approximately 351.02 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. This compound is highly reactive due to the presence of multiple electron-withdrawing groups, which can affect its reactivity in various chemical reactions. It is also known for its stability in air and light, but precautions should be taken during handling to avoid exposure to moisture and heat.

How is 5-Bromo-2-chloro-3-iodopyridine (CAS: 928653-73-0) typically synthesized?

5-Bromo-2-chloro-3-iodopyridine is typically synthesized via the substitution of chlorine and bromine in pyridine followed by iodination. Common synthetic routes involve the use of bromine and iodine in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is selective and yields a high percentage of the desired product, but proper handling of halogens and iodine is required to prevent side reactions and ensure safety.

What industries use 5-Bromo-2-chloro-3-iodopyridine (CAS: 928653-73-0)?

5-Bromo-2-chloro-3-iodopyridine finds applications in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also utilized in the development of sensors due to its unique spectral properties. Additionally, this compound may be used in semiconductor materials for its electronic properties. Its specific applications in these industries are limited, but it plays a crucial role in the research and development of advanced materials and pharmaceuticals.

What precautions should be taken when handling 5-Bromo-2-chloro-3-iodopyridine (CAS: 928653-73-0)?

When handling 5-Bromo-2-chloro-3-iodopyridine, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be used in a well-ventilated area or fume hood to minimize inhalation risks. Proper storage should be in a cool, dry place away from moisture and heat. In case of a spill, it is recommended to immediately clean up the area while wearing appropriate PPE and consult the Safety Data Sheet (SDS) for specific instructions. Exposure to this compound should be minimized due to its reactivity and potential health risks.