2',3'-Dideoxy-3'-fluoroguanosine | CAS No. 92562-88-4
2',3'-Dideoxy-3'-fluoroguanosine
Basic Information
CAS Number
92562-88-4
Molecular Formula
C10H12FN5O3
Molecular Weight
269.24 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- SCHEMBL914433
- GSK204937
- Lagociclovir [INN]
- 2',3'-DIDEOXY-3'-FLUORO-GUANOSINE
- SCHEMBL15531667
- 2',3'-Dideoxy-3'-fluoroguanosine
- 2-AMINO-9-(2,3-DIDEOXY-3-FLUORO-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ON
- MIV-210 (*Prodrug of FLG*)
- CS-3705
- NS00125133
- Guanosine, 2',3'-dideoxy-3'-fluoro-
- DTXSID90239044
- 2-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
- RTJUXLYUUDBAJN-KVQBGUIXSA-N
- 2', 3'-dideoxy-3'-fluoroguanosine
- HY-14844
- 2-amino-9-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
- 92562-88-4
- 2-amino-9-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
- UU109JJU0U
- 3'-fluoro-2',3'-dideoxyguanosine;2-amino-9-((2S,4R,5S)-4-fluoro-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
- 2-AMINO-9-[(2R,4S,5R)-4-FLUORO-5-(HYDROXYMETHYL)OXOLAN-2-YL]-1H-PURIN-6-ONE
- Fddguo
- 2',3'dideoxy-3'-fluoroguanosine
- 2',3'- dideoxy-3'- fluoroguanosine
- AKOS040741933
- AKOS025149452
- UNII-UU109JJU0U
- 3'-Fluoro-2',3'-dideoxyguanosine
- 3'-FddG
- MIV-210
MDL Number
MFCD00882020
FAQ
What are the physical and chemical properties of 2',3'-Dideoxy-3'-fluoroguanosine (CAS: 92562-88-4)?
2',3'-Dideoxy-3'-fluoroguanosine is a white to off-white crystalline powder. Its molecular weight is approximately 317.22 g/mol. This compound is poorly soluble in water but soluble in organic solvents like ethanol. It is not particularly reactive under normal conditions but can be sensitive to strong acids and bases. Its solubility and reactivity make it suitable for certain synthetic and biological applications.
How is 2',3'-Dideoxy-3'-fluoroguanosine (CAS: 92562-88-4) typically synthesized?
2',3'-Dideoxy-3'-fluoroguanosine can be synthesized by modifying the structure of guanosine through a series of chemical reactions. Common methods involve the use of nucleoside chemistry, where the 2'- and 3'-hydroxyl groups are selectively removed, followed by introduction of a fluorine atom at the 3' position. This process typically requires careful control of reaction conditions to achieve high yields and selectivity.
What industries use 2',3'-Dideoxy-3'-fluoroguanosine (CAS: 92562-88-4)?
2',3'-Dideoxy-3'-fluoroguanosine finds applications in pharmaceuticals, particularly in antiviral drug development. It is also used in research for studying nucleic acid analogs and their interactions with biological systems. This compound may also have potential applications in biotechnology, diagnostics, and materials science due to its unique chemical properties.
What precautions should be taken when handling 2',3'-Dideoxy-3'-fluoroguanosine (CAS: 92562-88-4)?
When handling 2',3'-Dideoxy-3'-fluoroguanosine, it is important to use personal protective equipment (PPE) such as gloves and lab coats. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled carefully using appropriate absorbent materials and should be cleaned up according to the Material Safety Data Sheet (MSDS/SDS). Ensure proper disposal of waste and follow all laboratory safety guidelines.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
