3,3-Difluorocyclohexanamine

Basic Information

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CAS Number

921753-34-6

Molecular Formula

C6H11F2N

Molecular Weight

135.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

141.186 °C at 760 mmHg

Density

1.086

Flash Point

141.186 °C at 760 mmHg

Refractive Index

1.422

SMILES

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C1CC(CC(C1)(F)F)N

InChI

InChI=1S/C6H11F2N/c7-6(8)3-1-2-5(9)4-6/h5H,1-4,9H2

InChIKey

VAQNIUDWPOLHBT-UHFFFAOYSA-N

LogP

1.523

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

103

Synonyms & References

English

EN300-82800
AM804552
3,3-Difluoro-cyclohexanamine
3,3-DIFLUOROCYCLOHEXANAMINE
SCHEMBL764676
AB85983
BS-13141
J-511073
MFCD12755815
AKOS015920422
DTXSID60694782
VAQNIUDWPOLHBT-UHFFFAOYSA-N
3,3-difluorocyclohexan-1-amine
AB86298
TRANS,TRANS-4-(4-PROPYLCYCLOHEXYL)-4-(4-ETHYLCYCLOHEXYL)-BIPHENYL
3,3-difluoro-cyclohexylamine
921753-34-6
FT-0733905
3,3-Difluorocyclohexanamine
3,3-Difluoro-cyclohexylamine
Cyclohexanamine, 3,3-difluoro-

MDL Number

MFCD12755815

Customs Code

2921300090

FAQ

What are the physical and chemical properties of 3,3-Difluorocyclohexanamine (CAS: 921753-34-6)?

3,3-Difluorocyclohexanamine (CAS: 921753-34-6) is a colorless liquid with a molecular weight of 132.11 g/mol. It has a low solubility in water but is readily soluble in organic solvents. It exhibits moderate reactivity, particularly in amine reactions. The compound is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is 3,3-Difluorocyclohexanamine (CAS: 921753-34-6) typically synthesized?

3,3-Difluorocyclohexanamine can be synthesized via the reduction of 3,3-difluorocyclohexanone with a suitable reducing agent such as sodium borohydride. The reaction is typically carried out in an aprotic solvent like tetrahydrofuran (THF) at room temperature. The yield is around 80% and the reaction is selective, producing the desired amine product with minimal side products.

What industries use 3,3-Difluorocyclohexanamine (CAS: 921753-34-6)?

3,3-Difluorocyclohexanamine (CAS: 921753-34-6) is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly those containing amine functionalities. It also finds applications in the production of polymers and as a precursor in the development of sensors and semiconductors.

What precautions should be taken when handling 3,3-Difluorocyclohexanamine (CAS: 921753-34-6)?

When handling 3,3-Difluorocyclohexanamine (CAS: 921753-34-6), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. In the event of a spill, avoid direct contact and clean up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.