Compound Q&A

How is 3,3-Difluorocyclohexanamine (CAS: 921753-34-6) typically synthesized?

Answer

3,3-Difluorocyclohexanamine
3,3-Difluorocyclohexanamine can be synthesized via the reduction of 3,3-difluorocyclohexanone with a suitable reducing agent such as sodium borohydride. The reaction is typically carried out in an aprotic solvent like tetrahydrofuran (THF) at room temperature. The yield is around 80% and the reaction is selective, producing the desired amine product with minimal side products.

About

English Name 3,3-Difluorocyclohexanamine
Molecular Formula C6H11F2N
Molecular Weight 135.16 g/mol
SMILES C1CC(CC(C1)(F)F)N
InChIKey VAQNIUDWPOLHBT-UHFFFAOYSA-N
Last Updated: 2026-01-02 00:31

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