Isobutyllithium

Basic Information

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CAS Number

920-36-5

Molecular Formula

C4H9Li

Molecular Weight

64.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Density

0.69

Flash Point

-4℃

SMILES

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[Li+].CC(C)[CH2-]

InChI

InChI=1S/C4H9.Li/c1-4(2)3;/h4H,1H2,2-3H3;

InChIKey

YZLMQRULZXAMEC-UHFFFAOYSA-N

LogP

1.2291999999999998

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

11.1

Safety Information

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GHS Hazard Pictograms

H225

H304

H314

H336

H410

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H304 May be fatal if swallowed and enters airways
Aspiration hazard

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H336 May cause drowsiness or dizziness
Specific target organ toxicity, single exposure; Narcotic effects

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Sensitiveness

对空气敏感，对湿度敏感

Synonyms & References

English

isobutyllithium solution
ISOBUTYLLITHIUM
Isobutyllithium, 1.6 M solution in Heptane, SpcSeal
lithium,2-methanidylpropane
IsobutyllithiuM, 1.6M solution in heptane, AcroSeal
Lithium, isobutyl- (6CI, 7CI, 8CI)
Isobutyllithium
CCZVEWRRAVASGL-UHFFFAOYSA-N
isobutyl lithium
lithium;2-methanidylpropane
i-BuLi
DTXSID50370563
AKOS015902194
i-butyllithium
EC 440-620-2
YZLMQRULZXAMEC-UHFFFAOYSA-N
920-36-5
(2-methylpropyl)lithium

MDL Number

MFCD01863085

Customs Code

29319090

FAQ

What regulatory guidelines apply to isobutyllithium (CAS: 920-36-5)?

Isobutyllithium (CAS: 920-36-5) must comply with the Globally Harmonized System (GHS) for classification and labeling of chemicals, REACH regulations for chemical substances in the European Union, and FDA/EPA requirements for the safe handling and storage. It is classified as a flammable liquid and requires specific safety measures such as fire prevention, ventilation, and the use of personal protective equipment.

Are there alternatives to isobutyllithium (CAS: 920-36-5) in synthesis?

While isobutyllithium is a powerful and widely used lithium reagent in organic synthesis, alternatives like sec-butyllithium and tert-butyllithium are available. These alternatives offer similar reactivity but may differ in stability and reactivity with specific substrates. It is crucial to evaluate the specific reaction conditions and desired product to choose the most suitable reagent.

What is the market or research trend for isobutyllithium (CAS: 920-36-5)?

The demand for isobutyllithium (CAS: 920-36-5) is driven by its use in the synthesis of various organic compounds and polymers. Research trends focus on its application in developing more efficient and environmentally friendly synthetic routes. Price trends show fluctuations based on supply and demand, with ongoing efforts to explore new applications and improve production methods.

How should waste containing isobutyllithium (CAS: 920-36-5) be handled?

Waste containing isobutyllithium (CAS: 920-36-5) should be collected in compatible containers, labeled appropriately, and disposed of according to local regulations. Professional waste disposal services are recommended for safe incineration or other environmentally friendly methods. Ensure proper ventilation and use personal protective equipment during handling to prevent exposure and minimize environmental impact.