Compound Q&A

Are there alternatives to isobutyllithium (CAS: 920-36-5) in synthesis?

Answer

Isobutyllithium
While isobutyllithium is a powerful and widely used lithium reagent in organic synthesis, alternatives like sec-butyllithium and tert-butyllithium are available. These alternatives offer similar reactivity but may differ in stability and reactivity with specific substrates. It is crucial to evaluate the specific reaction conditions and desired product to choose the most suitable reagent.

About

CAS No 920-36-5
English Name Isobutyllithium
Molecular Formula C4H9Li
Molecular Weight 64.06 g/mol
SMILES [Li+].CC(C)[CH2-]
InChIKey YZLMQRULZXAMEC-UHFFFAOYSA-N
Last Updated: 2025-10-17 17:23

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