(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid | CAS No. 919347-67-4

(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid

Basic Information

CAS Number

919347-67-4

Molecular Formula

C14H22BN3O4

Molecular Weight

307.16 g/mol

AD

Basic Physical Properties

B(C1=CN=C(C=C1)N2CCN(CC2)C(=O)OC(C)(C)C)(O)O

InChI

InChI=1S/C14H22BN3O4/c1-14(2,3)22-13(19)18-8-6-17(7-9-18)12-5-4-11(10-16-12)15(20)21/h4-5,10,20-21H,6-9H2,1-3H3

InChIKey

SYZMMRYQYWCLNC-UHFFFAOYSA-N

LogP

-0.18150000000000022

Topological Polar Surface Area

86.13000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

381

Synonyms & References

English

  • (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid
  • 6-(4-Boc-Piperazine-1-yl)pyridine-3- boronic acid
  • 2-(4-N-Boc-piperazino)pyridine-5-boronic acid
  • 6-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyridin-3-ylboronic acid
  • 6-(4-N-Boc-piperazin-1-yl)pyridine-3-boronic acid
  • 6-(4-N-Boc-Piperazine-1-yl)-3-pyridinyl boronic acid
  • [6-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]pyridin-3-yl]boronic acid
  • {6-[4-(tert-Butoxycarbonyl)piperazin-1-yl]pyridin-3-yl}boronic acid
  • SYZMMRYQYWCLNC-UHFFFAOYSA-N
  • AM87436
  • OR360100
  • AX8107641
  • V9150
  • CS
  • 1-(1,1-Dimethylethyl) 4-(5-borono-2-pyridinyl)-1-piperazinecarboxylate (ACI)
  • 2-(4-N-Boc-piperazino)pyridine-5-boronicacid
  • [6-[4-(tert-Butoxycarbonyl)piperazin-1-yl]pyridin-3-yl]boronic acid
  • (6-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid
  • FS-5212
  • 919347-67-4
  • [6-(4-{[(1,1-dimethylethyl)oxy]carbonyl}-1-piperazinyl)-3-pyridinyl]boronic acid
  • AKOS015837031
  • DB-089972
  • CS-0060952
  • 6-[4-(TERT-BUTOXYCARBONYL)PIPERAZIN-1-YL]PYRIDIN-3-YLBORONIC ACID
  • C14H22BN3O4
  • DB-079203
  • 6-(4-Boc-piperazine-1-yl)pyridine-3-boronic acid
  • DTXSID90681746
  • MFCD09952037
  • SCHEMBL1347359

MDL Number

MFCD09952037

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid (CAS: 919347-67-4)?

(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid is a crystalline compound with a molecular weight of approximately 438.47 g/mol. It has a solubility of 10 mg/mL in water and is only slightly soluble in common organic solvents. The compound shows moderate reactivity in the presence of acids and bases, and it is stable under normal laboratory conditions.

How is (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid (CAS: 919347-67-4) typically synthesized?

(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid is synthesized via a multi-step procedure involving the protection of a piperazine derivative followed by coupling with a pyridine boronic acid, using a suitable catalyst such as Pd(PPh3)4 under basic conditions. The yield is typically around 70-80%, with high selectivity to the desired product.

What industries use (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid (CAS: 919347-67-4)?

(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid is used in pharmaceutical research and development, particularly in the synthesis of complex organic molecules. It may also find applications in materials science, specifically in the development of new polymers and sensors.

What precautions should be taken when handling (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid (CAS: 919347-67-4)?

When handling (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be carried out in a well-ventilated area or a fume hood. Spills should be cleaned up with care, and the material safety data sheet (MSDS) should be consulted for specific spill procedures and disposal instructions.

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