Compound Q&A
How is (6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid (CAS: 919347-67-4) typically synthesized?
Answer
(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid is synthesized via a multi-step procedure involving the protection of a piperazine derivative followed by coupling with a pyridine boronic acid, using a suitable catalyst such as Pd(PPh3)4 under basic conditions. The yield is typically around 70-80%, with high selectivity to the desired product.
About
CAS No
919347-67-4
English Name
(6-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyridin-3-yl)boronic acid
Molecular Formula
C14H22BN3O4
Molecular Weight
307.16 g/mol
SMILES
B(C1=CN=C(C=C1)N2CCN(CC2)C(=O)OC(C)(C)C)(O)O
InChIKey
SYZMMRYQYWCLNC-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15
