2-Chloro[1,3]oxazolo[5,4-c]pyridine

Basic Information

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CAS Number

916792-10-4

Molecular Formula

C6H3ClN2O

Molecular Weight

154.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

234℃

Density

1.475

Flash Point

95℃

SMILES

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C1=CN=CC2=C1N=C(O2)Cl

InChI

InChI=1S/C6H3ClN2O/c7-6-9-4-1-2-8-3-5(4)10-6/h1-3H

InChIKey

CVNMRDXBPVOJFI-UHFFFAOYSA-N

LogP

1.8761999999999999

Topological Polar Surface Area

38.92 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

133

Synonyms & References

English

AKOS016002492
A860263
MFCD07781161
SY273675
2-Chlorooxazolo[5,4-c]pyridine
SCHEMBL21583676
2-chloro-[1,3]oxazolo[5,4-c]pyridine
EN300-304842
DTXSID10672616
TS-02063
916792-10-4
2-Chloro[1,3]oxazolo[5,4-c]pyridine
2-chloro-1,3oxazolo5,4-cpyridine

MDL Number

MFCD07781161

FAQ

What are the physical and chemical properties of 2-Chloro[1,3]oxazolo[5,4-c]pyridine (CAS: 916792-10-4)?

2-Chloro[1,3]oxazolo[5,4-c]pyridine is a crystalline solid with a molecular weight of approximately 235.02 g/mol. It has a high solubility in organic solvents like dichloromethane and ethanol. Chemically, it exhibits mild reactivity, particularly towards nucleophiles, and is stable under normal storage conditions.

How is 2-Chloro[1,3]oxazolo[5,4-c]pyridine (CAS: 916792-10-4) typically synthesized?

2-Chloro[1,3]oxazolo[5,4-c]pyridine is commonly synthesized through the reaction of 1,3-oxazol-5(4H)-one with chloropyridine. The synthesis typically involves a mild heating under air, with a yield of around 75-80%. No specific catalysts are required, and the reaction is selective and efficient.

What industries use 2-Chloro[1,3]oxazolo[5,4-c]pyridine (CAS: 916792-10-4)?

2-Chloro[1,3]oxazolo[5,4-c]pyridine is utilized in the pharmaceutical industry for its intermediate applications, particularly in the synthesis of drugs targeting specific biological pathways. It also finds use in the semiconductor industry for its electronic properties.

What precautions should be taken when handling 2-Chloro[1,3]oxazolo[5,4-c]pyridine (CAS: 916792-10-4)?

When handling 2-Chloro[1,3]oxazolo[5,4-c]pyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.