2-Chloro[1,3]oxazolo[5,4-c]pyridine(CAS: 916792-10-4)

2-Chloro[1,3]oxazolo[5,4-c]pyridine is a crystalline solid with a molecular weight of approximately 235.02 g/mol. It has a high solubility in organic solvents like dichloromethane and ethanol. Chemically, it exhibits mild reactivity, particularly towards nucleophiles, and is stable under normal storage conditions.

2-Chloro[1,3]oxazolo[5,4-c]pyridine is commonly synthesized through the reaction of 1,3-oxazol-5(4H)-one with chloropyridine. The synthesis typically involves a mild heating under air, with a yield of around 75-80%. No specific catalysts are required, and the reaction is selective and efficient.

2-Chloro[1,3]oxazolo[5,4-c]pyridine is utilized in the pharmaceutical industry for its intermediate applications, particularly in the synthesis of drugs targeting specific biological pathways. It also finds use in the semiconductor industry for its electronic properties.

When handling 2-Chloro[1,3]oxazolo[5,4-c]pyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.