2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (1:1:1) | CAS No. 915769-50-5
2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (1:1:1)
Basic Information
CAS Number
915769-50-5
Molecular Formula
C24H29FN6O5
Molecular Weight
500.53 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydrate
- 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-hydroxypropanoate hydrate (1:1:1)
- Dovitinib lactate
- Dovitinib
- CHIR-258 (TKI-258,Dovitinib)
- Unii-69vky8p7ea
- Dovitinib lactate hydrate
- TKI 258 lactate
MDL Number
MFCD16038433
FAQ
What are the physical and chemical properties of 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (CAS: 915769-50-5)?
This compound has a crystalline form and a molecular weight of approximately 753.75 g/mol. It is slightly soluble in water and exhibits low reactivity under normal conditions. The hydrate form increases its solubility. It is stable in air and light, but should be stored in a dry, cool place away from strong acids and bases.
How is 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (CAS: 915769-50-5) typically synthesized?
This compound is synthesized by a multi-step process involving condensation reactions, amidation, and quinoline ring formation. The synthesis typically requires the use of specific catalysts and reagents. The yield is around 70-80%, with good selectivity for the desired product.
What industries use 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (CAS: 915769-50-5)?
This compound is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various bioactive compounds. It may also have applications in the polymer industry for specific functional polymers, and in the development of advanced sensors and semiconductors.
What precautions should be taken when handling 2-Hydroxypropanoic acid - 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone hydrate (CAS: 915769-50-5)?
When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be performed in a well-ventilated area or fume hood. Spills should be cleaned up immediately and handled in accordance with the safety data sheet (SDS). Ensure proper storage in a cool, dry place away from heat sources and incompatible materials.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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