3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide | CAS No. 915385-81-8
3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide
Basic Information
CAS Number
915385-81-8
Molecular Formula
C23H25ClN2O
Molecular Weight
380.91 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- ABC294640
- Opaganib
- ABC 294640
- Opaganib (ABC294640)
- 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide
- DRG21OQ517
- Yeliva
- GTPL6624
- HMS3402P05
- BCP08959
- BDBM50393642
- SB17167
- DB12764
- API0017247
- S7174
- Q27074100
- (1s,3r,5R,7S)-3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxami
- 3-(4-Chlorophenyl)-N-(4-pyridinylmethyl)tricyclo[3.3.1.13,7]decane-1-carboxamide (ACI)
- 4-PYRIDINYLMETHYL 3(4-CHLOROPHENYL)ADAMANTINE CARBOXAMIDE
- CCG-268417
- (1s,3r,5R,7S)-3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide
- SCHEMBL1548333
- OPAGANIB [INN]
- CS-0877
- EX-A1962
- HY-16015
- CHEBI:124965
- BRD-A70814879-003-02-6
- BRD-A70814879-001-01-2
- DTXSID801318727
- ABC294640Opaganib?
MDL Number
MFCD22666355
FAQ
What are the physical and chemical properties of 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide (CAS: 915385-81-8)?
3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide is a crystalline solid with a molecular weight of approximately 393.14 g/mol. It has a low water solubility and is moderately soluble in common organic solvents like DMSO and acetonitrile. Chemically, it is relatively stable under normal conditions but may react with strong bases or reducing agents. It has a pKa of about 7.5 and a melting point of around 180-185°C.
How is 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide (CAS: 915385-81-8) typically synthesized?
3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide is synthesized through a multi-step process involving the condensation of 4-chlorophenyl acetic acid with 1-adamantanecarboxylic acid, followed by coupling with 4-pyridylmethylamine. The process requires careful control of pH and temperature to achieve high yield and selectivity. The method typically involves the use of catalytic amounts of a base like triethylamine and a coupling reagent such as HATU or EDC. The final step is purification by column chromatography.
What industries use 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide (CAS: 915385-81-8)?
3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide is primarily used in the pharmaceutical industry for its potential as a drug candidate. It may also find applications in the development of sensors and semiconductors due to its unique chemical structure and electronic properties. Further research is ongoing to explore its use in polymer synthesis and other advanced materials.
What precautions should be taken when handling 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide (CAS: 915385-81-8)?
When handling 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide, safety measures include wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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