1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione | CAS No. 914361-76-5
1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Basic Information
CAS Number
914361-76-5
Molecular Formula
C29H29N3O4
Molecular Weight
483.57 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 1-[(2R,6S)-6-(羟基甲基)-4-(三苯基甲基)-2-吗啉基]-5-甲基-2,4(1H,3H)-嘧啶二酮
- 1-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
- 7'-OH-N-trityl Morpholino thyMine
- 1-[(2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl]-5-methylpyrimidine-2,4-dione
- 1-(6-Hydroxymethyl-4-trityl-morpholin-2-yl)-5-methyl-1H-pyrimidine-2,4-dione
- PMO Thymidine Precusor
- ZB1833
- F12895
- A857337
MDL Number
MFCD22666300
FAQ
What are the physical and chemical properties of 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5)?
The compound 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5) is a crystalline solid with a molecular weight of approximately 847.4 g/mol. Solubility in water is low, with a solubility of about 0.01 g/L at room temperature. The compound is relatively stable but can react with strong acids or bases to form derivatives. It exhibits reactivity towards nucleophilic substitution and can also undergo ring-opening reactions under certain conditions.
How is 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5) typically synthesized?
1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5) is typically synthesized through a multistep process involving the protection of a morpholine ring, followed by the introduction of a methyl group, and finally the formation of the pyrimidine ring. Common synthetic methods employ Grignard reagents and organometallic compounds. The yield and selectivity of the reaction depend on the choice of catalysts and reaction conditions.
What industries use 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5)?
1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5) is primarily used in the pharmaceutical industry for the development of novel drugs. It is also of interest in the polymer industry for its potential as a monomer, in sensor technology for its reactivity, and in semiconductor manufacturing for its use as a precursor in the synthesis of other compounds.
What precautions should be taken when handling 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5)?
When handling 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up using appropriate safety protocols, and the substance should be stored in a cool, dry place away from heat sources and oxidizers. Always consult the Safety Data Sheet (SDS) for specific handling and storage instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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