Compound Q&A
How is 1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5) typically synthesized?
Answer
![1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione](https://static.chemtradehub.com/structs/914/914361-76-5-c292.webp "1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione")
1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 914361-76-5) is typically synthesized through a multistep process involving the protection of a morpholine ring, followed by the introduction of a methyl group, and finally the formation of the pyrimidine ring. Common synthetic methods employ Grignard reagents and organometallic compounds. The yield and selectivity of the reaction depend on the choice of catalysts and reaction conditions.
About
CAS No
914361-76-5
English Name
1-[(2R,6S)-6-(Hydroxymethyl)-4-trityl-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Molecular Formula
C29H29N3O4
Molecular Weight
483.57 g/mol
SMILES
O=C1NC(C(C)=CN1[C@H]2CN(C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C[C@@H](CO)O2)=O
InChIKey
SINOYLIIFJJPCM-IZZNHLLZSA-N
Last Updated: 2026-03-08 00:27
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