R788 disodium hexahydrate

Basic Information

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CAS Number

914295-16-2

Molecular Formula

C23H36FN6Na2O15P

Molecular Weight

732.51 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Insecticides

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]

InChI

InChI=1S/C23H26FN6O9P.2Na.6H2O/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;;;;;;;/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29);;;6*1H2/q;2*+1;;;;;;/p-2

InChIKey

ZQGJCHHKJNSPMS-UHFFFAOYSA-L

LogP

3.24120

Complexity

893

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one disodium salt hexahydrate
Fostamatinib Disodium Hexahydrate
R788 disodium hexahydrate
R788 (disodium hexahydrate)
R-788 disodium hexahydrate
86EEZ49YVB
R 788 sodium
Fostamatinib disodium [USAN]
R 935788 sodium
Tamatinib fosdium
Fostamatinib disodium (USAN)
R788 SODIUM
R935788 SODIUM
Tavalisse (TN)
R935788
R788 SODIUM HYDRATE
ZQGJCHHKJNSPMS-UHFFFAOYSA-L
R935788 SODIUM HYDRATE
BCP14298
C23H24FN6O9P.2Na.6H2O
2417AH
Fostamatinib disod
disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate;hexahydrate
Fostamatinib disodium
2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, disodium salt, hexahydrate (9CI)
Fostamatinib disodium hexahydrate
Tavalisse
Sodium (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)methyl phosphate hexahydrate
R-935788
SB40416
FOSTAMATINIB DISODIUM [WHO-DD]

MDL Number

MFCD15146370

FAQ

What is R788 disodium hexahydrate (CAS: 914295-16-2)?

R788 disodium hexahydrate (CAS: 914295-16-2) is a compound with a chemical formula of C13H18N4Na2O10·6H2O. It is a white or off-white solid at room temperature, with a melting point of approximately 180°C. This compound is primarily used in pharmaceuticals for its potential anti-inflammatory and antitumor activities.

What are the main uses of R788 disodium hexahydrate (CAS: 914295-16-2)?

R788 disodium hexahydrate (CAS: 914295-16-2) is mainly used in pharmaceutical research for its potential therapeutic effects, particularly in the treatment of inflammatory and tumor-related diseases. It is also used in some laboratory settings for biological assays and studies.

Is R788 disodium hexahydrate (CAS: 914295-16-2) safe?

R788 disodium hexahydrate (CAS: 914295-16-2) is considered generally safe when handled correctly. However, it should be used with caution, especially when in contact with skin or eyes. Proper protective measures such as gloves and goggles should be worn, and it should be stored away from heat and direct sunlight.

How should R788 disodium hexahydrate (CAS: 914295-16-2) be stored?

R788 disodium hexahydrate (CAS: 914295-16-2) should be stored in a cool, dry place, away from direct sunlight and sources of heat. It should be kept in a tightly sealed container to prevent moisture absorption. The storage temperature should not exceed 30°C to maintain its stability.