1-[3-(1-Piperidinylmethyl)phenyl]methanamine | CAS No. 91271-80-6
1-[3-(1-Piperidinylmethyl)phenyl]methanamine
Basic Information
CAS Number
91271-80-6
Molecular Formula
C13H20N2
Molecular Weight
204.32 g/mol
AD
Basic Physical Properties
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- SCHEMBL111526
- 3-Piperidin-1-ylmethyl)phenyl]methanamine
- 91271-80-6
- SB39852
- [3-(PIPERIDINOMETHYL)PHENYL]METHANAMINE
- EN300-64264
- DTXSID50383315
- FT-0694243
- 3-piperidin-1-ylmethyl benzylamine, AldrichCPR
- [3-(piperidin-1-ylmethyl)phenyl]methanamine
- CS-0271827
- 3-Piperidin-1-ylmethyl-benzylamine
- TS-01501
- (3-(Piperidin-1-ylmethyl)phenyl)methanamine
- AKOS000137498
- {3-[(piperidin-1-yl)methyl]phenyl}methanamine
- 1-[3-(piperidin-1-ylmethyl)phenyl]methanamine
- BMNFPARGJHNMAX-UHFFFAOYSA-N
- 7-Acetylbenzofuran
- 3-Piperidin-1-ylmethyl benzylamine
- 1-[3-(PIPERIDIN-1-YLMETHYL)PHENYL]METHANAMINE
- Benzenemethanamine,3-(1-piperidinylmethyl)-
- [3-(piperidylmethyl)phenyl]methylamine
MDL Number
MFCD06408781
Customs Code
2933399090
FAQ
What are the physical and chemical properties of 1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6)?
1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6) is a crystalline compound with a molecular weight of approximately 244.34 g/mol. It has a pKa of about 8.9 and can be soluble in organic solvents like methanol and ethanol. This compound is amphoteric, showing moderate reactivity in base-catalyzed reactions. It is stable under normal conditions but should be stored away from strong acids and bases to prevent degradation.
How is 1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6) typically synthesized?
1-[3-(1-Piperidinylmethyl)phenyl]methanamine can be synthesized via a multi-step process involving amination of a substituted benzene, followed by reaction with piperidine. Commonly, a palladium-catalyzed cross-coupling reaction is used for the amination step. The overall yield can be around 60-70%, with good selectivity towards the desired product. Detailed procedures can be found in scientific literature and patents.
What industries use 1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6)?
1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the polymer industry as a monomer for producing certain types of plastics and resins. Additionally, it can be used in the development of sensors and as a building block in the synthesis of semiconductors.
What precautions should be taken when handling 1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6)?
When handling 1-[3-(1-Piperidinylmethyl)phenyl]methanamine (CAS: 91271-80-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound should be stored in a well-ventilated area, away from strong acids and bases. In case of a spill, it should be cleaned up immediately using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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