2-Chloro-3-iodopyridin-4-amine

Basic Information

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CAS Number

909036-46-0

Molecular Formula

C5H4ClIN2

Molecular Weight

254.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

116-117℃

Boiling Point

377°C at 760 mmHg

SMILES

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C1=CN=C(C(=C1N)I)Cl

InChI

InChI=1S/C5H4ClIN2/c6-5-4(7)3(8)1-2-9-5/h1-2H,(H2,8,9)

InChIKey

BYVMKCHHWASQFN-UHFFFAOYSA-N

LogP

1.9218

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

101

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Light Sensitive

Synonyms & References

English

2-Chloro-3-iodopyridin-4-amine
4-Amino-2-chloro-3-iodopyridine
2-Chloro-3-iodo-pyridin-4-ylamine
4-Pyridinamine,2-chloro-3-iodo-
2-chloro-3-iodo-4-aminopyridine
2-chloro-3-iodo-4-pyridinamine
2-chloro-3-iodo-4-pyridylamine
2-chloro-3-iodo-pyridin-4-yl-amine
PubChem22625
BYVMKCHHWASQFN-UHFFFAOYSA-N
2-chloro-3-iodopyridin-4-ylamine
BCP18369
STL557424
SBB101452
KM2946
BBL103614
SB21081
OR42029
FCH1393340
MC
2-Chloro-3-iodo-4-pyridinamine (ACI)
2-Chloro-3-iodopyridin-4-ylamine
2-chloro-3-iodopyridin-4-amine
SY041724
909036-46-0
2-Chloro-3-iodo-4-aminopyridine
EN300-192330
2-Chloro-3-iodopyridin-4-amine, AldrichCPR
DTXSID70640098
AKOS005073253
DB-000461

MDL Number

MFCD09763660

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Chloro-3-iodopyridin-4-amine (CAS: 909036-46-0)?

2-Chloro-3-iodopyridin-4-amine, CAS 909036-46-0, is a crystalline solid with a molecular weight of approximately 302.0 g/mol. It is sparingly soluble in water but more soluble in organic solvents like DMSO and DMF. This compound is known for its low reactivity under normal conditions but can undergo substitution reactions under specific conditions.

How is 2-Chloro-3-iodopyridin-4-amine (CAS: 909036-46-0) typically synthesized?

2-Chloro-3-iodopyridin-4-amine is typically synthesized via the reaction of 2-chloropyridin-4-amine with iodine in the presence of a base such as sodium hydroxide. This synthesis results in a high yield with good selectivity, making it a preferred method in the preparation of this compound.

What industries use 2-Chloro-3-iodopyridin-4-amine (CAS: 909036-46-0)?

2-Chloro-3-iodopyridin-4-amine is primarily used in the pharmaceutical industry for the development of novel drug candidates. It also finds applications in the synthesis of organic semiconductors and as a reagent in various chemical processes due to its unique chemical functionality.

What precautions should be taken when handling 2-Chloro-3-iodopyridin-4-amine (CAS: 909036-46-0)?

When handling 2-Chloro-3-iodopyridin-4-amine, it is important to use personal protective equipment (PPE) such as gloves and goggles. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Immediate action should be taken in case of spills, following the Safety Data Sheet (SDS) guidelines for clean-up and disposal.