2-Chloro-3-iodopyridin-4-amine(CAS: 909036-46-0)

2-Chloro-3-iodopyridin-4-amine, CAS 909036-46-0, is a crystalline solid with a molecular weight of approximately 302.0 g/mol. It is sparingly soluble in water but more soluble in organic solvents like DMSO and DMF. This compound is known for its low reactivity under normal conditions but can undergo substitution reactions under specific conditions.

2-Chloro-3-iodopyridin-4-amine is typically synthesized via the reaction of 2-chloropyridin-4-amine with iodine in the presence of a base such as sodium hydroxide. This synthesis results in a high yield with good selectivity, making it a preferred method in the preparation of this compound.

2-Chloro-3-iodopyridin-4-amine is primarily used in the pharmaceutical industry for the development of novel drug candidates. It also finds applications in the synthesis of organic semiconductors and as a reagent in various chemical processes due to its unique chemical functionality.

When handling 2-Chloro-3-iodopyridin-4-amine, it is important to use personal protective equipment (PPE) such as gloves and goggles. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Immediate action should be taken in case of spills, following the Safety Data Sheet (SDS) guidelines for clean-up and disposal.