4-Chloro-N-cyclopropyl-3-nitrobenzamide

Basic Information

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CAS Number

90797-58-3

Molecular Formula

C10H9ClN2O3

Molecular Weight

240.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

399.9°Cat760mmHg

Density

1.45

Flash Point

195.6°C

Refractive Index

1.616

SMILES

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C1CC1NC(=O)C2=CC(=C(C=C2)Cl)[N+](=O)[O-]

InChI

InChI=1S/C10H9ClN2O3/c11-8-4-1-6(5-9(8)13(15)16)10(14)12-7-2-3-7/h1,4-5,7H,2-3H2,(H,12,14)

InChIKey

ZUWRELJOMFUPGP-UHFFFAOYSA-N

Complexity

301

Synonyms & References

English

4-chloro-N-cyclopropyl-3-nitro-benzamide
DTXSID10358221
CS-0242985
SR-01000234075
4-chloro-n-cyclopropyl-3-nitrobenzamide
SR-01000234075-1
Oprea1_057783
LS-07308
AB00107387-01
MFCD02640862
90797-58-3
Z30841038
AKOS000119048
ZUWRELJOMFUPGP-UHFFFAOYSA-N
SCHEMBL2224151
EN300-25756
Benzamide,4-chloro-N-cyclopropyl-3-nitro-
4-CHLORO-N-CYCLOPROPYL-3-NITROBENZAMIDE

MDL Number

MFCD02640862

FAQ

What are the physical and chemical properties of 4-Chloro-N-cyclopropyl-3-nitrobenzamide (CAS: 90797-58-3)?

4-Chloro-N-cyclopropyl-3-nitrobenzamide is a crystalline solid with a molecular weight of approximately 214.6 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards reducing agents and nucleophiles. It is also sensitive to light and may decompose under strong acidic or basic conditions.

How is 4-Chloro-N-cyclopropyl-3-nitrobenzamide (CAS: 90797-58-3) typically synthesized?

4-Chloro-N-cyclopropyl-3-nitrobenzamide is synthesized through a multi-step process involving nitration and alkylation reactions. Commonly, 3-nitrobenzoic acid is first alkylated with cyclopropyl chloride to form the corresponding amide. The synthesis typically requires the use of Lewis acids and requires careful control of reaction conditions to achieve high yields and selectivity.

What industries use 4-Chloro-N-cyclopropyl-3-nitrobenzamide (CAS: 90797-58-3)?

4-Chloro-N-cyclopropyl-3-nitrobenzamide is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the polymer industry for the development of advanced materials and sensors. Additionally, it can be used in the electronics industry for semiconductor applications due to its unique chemical properties.

What precautions should be taken when handling 4-Chloro-N-cyclopropyl-3-nitrobenzamide (CAS: 90797-58-3)?

When handling 4-Chloro-N-cyclopropyl-3-nitrobenzamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be stored in a cool, dry place away from direct sunlight and heat sources. Fume hoods should be used during handling to minimize exposure to fumes. In case of a spill, it is recommended to clean up using appropriate methods and to consult a Material Safety Data Sheet (MSDS) for detailed instructions.