2-(Pyridin-2-yl)cyclopropanecarboxylic acid

Basic Information

View in Editor

CAS Number

90563-75-0

Molecular Formula

C9H9NO2

Molecular Weight

163.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

97-99 ºC (benzene ligroine )

Boiling Point

352.0±35.0℃/760mmHg

Density

1.327±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

View in Editor

C1C(C1C(=O)O)C2=CC=CC=N2

InChI

InChI=1S/C9H9NO2/c11-9(12)7-5-6(7)8-3-1-2-4-10-8/h1-4,6-7H,5H2,(H,11,12)

InChIKey

ZFZMEVZZAIRAHE-UHFFFAOYSA-N

LogP

1.2697

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

193

Synonyms & References

English

2-(2-pyridinyl)-Cyclopropanecarboxylic acid,
2-(2-Pyridyl)cyclopropanecarboxylic Acid
(1S,2S)-2-(pyridin-2-yl)cyclopropanecarboxylic acid
2-(Pyridin-2-yl)cyclopropanecarboxylic acid
2-PYRIDIN-2-YL-CYCLOPROPANECARBOXYLIC ACID
2-pyridin-2-ylcyclopropane-1-carboxylic acid
2-(pyridin-2-yl)cyclopropane-1-carboxylic acid
(1R,2R)-2-(Pyridin-2-yl)cyclopropanecarboxylic acid
ZFZMEVZZAIRAHE-UHFFFAOYSA-N
1279AJ
TRA0023242
2-(2-Pyridyl)cyclopropanecarboxylicAcid
AK155239
SY033158
ST24039744
2-Pyridi
2-(2-Pyridinyl)cyclopropanecarboxylic acid (ACI)
Cyclopropanecarboxylic acid, 2-(2-pyridyl)- (7CI)
2-(Pyridin-2-yl)cyclopropane-1-carboxylic acid
(1S,2S)-rel-2-(Pyridin-2-yl)cyclopropane-1-carboxylic acid
2-Pyridin-2-yl-cyclopropanecarboxylic acid
DB-261420
1287205-75-7
Y10094
AC-29519
SB39771
AKOS009997088
MFCD20640560
2-(2-Pyridinyl)-cyclopropanecarboxylic acid
SCHEMBL1207556
2-(pyridin-2-yl)cyclopropanecarboxylicacid

MDL Number

MFCD08456944

FAQ

What are the physical and chemical properties of 2-(Pyridin-2-yl)cyclopropanecarboxylic acid (CAS: 90563-75-0)?

2-(Pyridin-2-yl)cyclopropanecarboxylic acid is a solid with a crystalline form at room temperature. Its molecular weight is approximately 175.16 g/mol. The compound is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It exhibits moderate reactivity, particularly in amide formation and nucleophilic substitution reactions.

How is 2-(Pyridin-2-yl)cyclopropanecarboxylic acid (CAS: 90563-75-0) typically synthesized?

2-(Pyridin-2-yl)cyclopropanecarboxylic acid can be synthesized via a multi-step reaction involving the coupling of cyclopropanecarboxylic acid chloride and 2-bromopyridine. This reaction is typically carried out in the presence of a base like triethylamine. The yield is around 80%, and the method ensures good selectivity and purity.

What industries use 2-(Pyridin-2-yl)cyclopropanecarboxylic acid (CAS: 90563-75-0)?

2-(Pyridin-2-yl)cyclopropanecarboxylic acid is utilized in the pharmaceutical industry for the synthesis of drugs that require specific functional groups. It is also used in the polymer industry for modifying polymer properties and in the sensor industry for its reactivity towards various analytes.

What precautions should be taken when handling 2-(Pyridin-2-yl)cyclopropanecarboxylic acid (CAS: 90563-75-0)?

When handling 2-(Pyridin-2-yl)cyclopropanecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.