Chymotrypsin Substrate I, Colorimetric

Basic Information

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CAS Number

9004-07-3

Molecular Formula

C23H25N5O8

Molecular Weight

499.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

127 ºC

Density

1.0470

Solubility

Reconstitute in 1mM HCl. Soluble at 10mg/ml in 1mM HCl. 2mM calcium chloride serves as a stabilizer. Store aliquoted solutions at -20°C for up to a week.

SMILES

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C1=CC=C(C=C1)CC(C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CNC(=O)CNC(=O)CCC(=O)O

InChI

InChI=1S/C23H25N5O8/c29-19(10-11-22(32)33)24-13-20(30)25-14-21(31)27-18(12-15-4-2-1-3-5-15)23(34)26-16-6-8-17(9-7-16)28(35)36/h1-9,18H,10-14H2,(H,24,29)(H,25,30)(H,26,34)(H,27,31)(H,32,33)

InChIKey

CFYIUBWVKZQDOG-UHFFFAOYSA-N

Complexity

36.8

Safety Information

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GHS Hazard Pictograms

H315

H319

H334

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

易潮湿

Synonyms & References

English

Chymotrypsin
alphachymar
alpha-chymarophth
alpha-chymotrypsinfrombovinepancreas
avazyme
catarase
chymar
chymolase
alpha-ChyMotrypsin, USP grade
α-Chymotrypsin from bovine pancreas(TLCK Treated,Sequence)
A-CHYMOTRYPSIN
1000 usp u
800 usp u
Chymotrypsin(bovine)
Crotyl alcohol, Mixture of cis and trans
α-Chymotrypsin(bovine)
TLCK-Chymotrypsin
alpha-Chymotrypsin
α-Chymotrypsin
N-Succinyl-Gly-Gly-Phe-p-nitroanilide
CFYIUBWVKZQDOG-UHFFFAOYSA-N
a-Chymotrypsin
N-(3-Carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-L-phenylalaninamide
DB-055212
Chymotrypsin Substrate I, Colorimetric
CHYMOTRYPSIN
4-Hydroxy-4-({2-hydroxy-2-[(2-hydroxy-2-{[1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]imino}ethyl)imino]ethyl}imino)butanoic acid
PD166954
4-[[2-[[2-[[1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-oxobutanoic acid
3-[({[({1-[(4-nitrophenyl)carbamoyl]-2-phenylethyl}carbamoyl)methyl]carbamoyl}methyl)carbamoyl]propanoic acid
G75957

MDL Number

MFCD00130481

Customs Code

35079090

FAQ

What are the physical and chemical properties of Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3)?

Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3) is a crystalline compound with a molecular weight of approximately 549.3 g/mol. It is soluble in water and slightly soluble in ethanol. This substrate exhibits high reactivity towards chymotrypsin, producing a colorimetric signal that can be measured spectrophotometrically.

How is Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3) typically synthesized?

Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3) is synthesized by coupling a chromogenic amino acid derivative to a chymotrypsin recognition motif. Commonly, this involves using a protected amino acid and a coupling reagent such as N,N′-carbodiimide in the presence of a suitable catalyst to achieve high yield and selectivity.

What industries use Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3)?

Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3) is widely used in the pharmaceutical industry for enzyme activity assays and in the food and beverage industry for quality control of proteolytic processes. It is also utilized in research for studying protease activities and in diagnostic applications.

What precautions should be taken when handling Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3)?

When handling Chymotrypsin Substrate I, Colorimetric (CAS: 9004-07-3), it is essential to wear appropriate personal protective equipment (PPE) including gloves and goggles. Work should be conducted in a well-ventilated area or fume hood. In case of spill, immediately use a suitable absorbent material and follow the safety data sheet (SDS) for further cleanup instructions.