2-(Pyridin-3-yl)propanoic acid

Basic Information

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CAS Number

90005-62-2

Molecular Formula

C8H9NO2

Molecular Weight

151.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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CC(C1=CN=CC=C1)C(=O)O

InChI

InChI=1S/C8H9NO2/c1-6(8(10)11)7-3-2-4-9-5-7/h2-6H,1H3,(H,10,11)

InChIKey

RVSGAPGURIPIFA-UHFFFAOYSA-N

LogP

1.2697

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

147

Synonyms & References

English

a-methyl-3-Pyridineacetic acid
2-Pyridin-3-yl-propionic acid
3-Pyridineacetic acid, α-methyl-
α-Methyl-3-pyridineacetic acid (ACI)
2-(Pyridin-3-yl)propanoic acid
α-Methylpyridine-3-acetic acid
2-(pyridin-3-yl)propanoic acid
90005-62-2
DTXSID301305296
EN300-68926
3-Pyridineacetic acid, a-methyl-
SCHEMBL22364681
I+/--Methyl-3-pyridineacetic acid
2-pyridin-3-ylpropanoic Acid
2-(pyridin-3-yl)propanoicacid
SB53937
BS-13516
2-pyridin-3-yl-propionic acid
SCHEMBL575045
MFCD14585027
AKOS010488654
DB-002474
Z792377268
3-pyridylpropanoic acid

MDL Number

MFCD14585027

FAQ

What are the physical and chemical properties of 2-(Pyridin-3-yl)propanoic acid (CAS: 90005-62-2)?

2-(Pyridin-3-yl)propanoic acid is a solid at room temperature with a crystalline form. It has a molecular weight of approximately 156.16 g/mol and is moderately soluble in water. This compound exhibits acidity and can participate in esterification reactions. It is stable under normal storage conditions but should be protected from strong bases and oxidizing agents.

How is 2-(Pyridin-3-yl)propanoic acid (CAS: 90005-62-2) typically synthesized?

2-(Pyridin-3-yl)propanoic acid can be synthesized via a multi-step process starting from 3-chloropropanoic acid. The reaction involves nucleophilic substitution followed by a condensation reaction with pyridine. Commonly, this process uses catalysis with a phase transfer catalyst and may involve selective use of solvents to enhance yield and purity.

What industries use 2-(Pyridin-3-yl)propanoic acid (CAS: 90005-62-2)?

2-(Pyridin-3-yl)propanoic acid finds applications in the pharmaceutical industry for the synthesis of various drugs. It is also used in the sensor industry for developing chemical sensors due to its specific reactivity. Additionally, it plays a role in the production of certain polymers and is explored in the field of semiconductors for its electronic properties.

What precautions should be taken when handling 2-(Pyridin-3-yl)propanoic acid (CAS: 90005-62-2)?

When handling 2-(Pyridin-3-yl)propanoic acid, it is important to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. It should be stored in a fume hood to prevent exposure. In case of a spill, it should be cleaned up with caution using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.