2-(Pyridin-3-yl)propanoic acid(CAS: 90005-62-2)

2-(Pyridin-3-yl)propanoic acid is a solid at room temperature with a crystalline form. It has a molecular weight of approximately 156.16 g/mol and is moderately soluble in water. This compound exhibits acidity and can participate in esterification reactions. It is stable under normal storage conditions but should be protected from strong bases and oxidizing agents.

2-(Pyridin-3-yl)propanoic acid can be synthesized via a multi-step process starting from 3-chloropropanoic acid. The reaction involves nucleophilic substitution followed by a condensation reaction with pyridine. Commonly, this process uses catalysis with a phase transfer catalyst and may involve selective use of solvents to enhance yield and purity.

2-(Pyridin-3-yl)propanoic acid finds applications in the pharmaceutical industry for the synthesis of various drugs. It is also used in the sensor industry for developing chemical sensors due to its specific reactivity. Additionally, it plays a role in the production of certain polymers and is explored in the field of semiconductors for its electronic properties.

When handling 2-(Pyridin-3-yl)propanoic acid, it is important to wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. It should be stored in a fume hood to prevent exposure. In case of a spill, it should be cleaned up with caution using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.