3'-Amino-2'-hydroxyacetophenone hydrochloride

Basic Information

View in Editor

CAS Number

90005-55-3

Molecular Formula

C8H10ClNO2

Molecular Weight

187.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

226-233°C (dec.)

Boiling Point

287.2 ºC at 760 mmHg

Flash Point

127.5 ºC

SMILES

View in Editor

CC(=O)C1=C(C(=CC=C1)N)O.Cl

InChI

InChI=1S/C8H9NO2.ClH/c1-5(10)6-3-2-4-7(9)8(6)11;/h2-4,11H,9H2,1H3;1H

InChIKey

BSWMUKIPTBQFPN-UHFFFAOYSA-N

LogP

1.5987999999999998

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

158

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3'-Amino-2'-hydroxyacetophenone hydrochloride
1-(3-AMINO-2-HYDROXY-PHENYL)-ETHANONE
1-(3-AMINO-2-HYDROXY-PHENYL)-ETHANONE HYDROCHLORIDE
3-AMINO-2-HYDROXYACETOPHENONE HCL
3-AMINO-2-HYDROXYACETOPHENONE HYDROCHLORIDE
2'-hydroxy-3'-aminoacetophenone hydrochloride
Ethanone, 1-(3-amino-2-hydroxyphenyl)-, hydrochloride (1:1)
3'-Amino-2'-hydroxya
3´-Amino-2´-hydroxyacetophenone Hydrochloride
1-(3-amino-2-hydroxyphenyl)ethanone,hydrochloride
3?-Amino-2?-hydroxyacetophenone Hydrochloride
3'-AMino-2'-hydroxyacetophenone, HCl
Acetophenone,3'-amino-2'-hydroxy-, hydrochloride (7CI)
Ethanone,1-(3-amino-2-hydroxyphenyl)-, hydrochloride (9CI)
2-Acetyl-6-aminophenolhydrochloride
Acetophenone, 3′-amino-2′-hydroxy-, hydrochloride (7CI)
Ethanone, 1-(3-amino-2-hydroxyphenyl)-, hydrochloride (9CI)
1-(3-Amino-2-hydroxyphenyl)ethan-1-one hydrochloride
2-Acetyl-6-aminophenol hydrochloride
3′-Amino-2′-hydroxyacetophenone hydrochloride
1-(3-amino-2-hydroxyphenyl)ethanone hydrochloride
SY109598
1-(3-Amino-2-hydroxyphenyl)ethan-1-one--hydrogen chloride (1/1)
MFCD03790987
1-(3-amino-2-hydroxyphenyl)ethanone;hydrochloride
DB-023145
3-Amino-2-hydroxyacetophenone, hydrochloride
AKOS015951165
1-(3-Amino-2-hydroxy-phenyl)-ethanone hydrochloride
3-Amino-2-hydroxyacetophenone Hydrochloride
Ethanone, 1-(3-amino-2-hydroxyphenyl)-, hydrochloride

MDL Number

MFCD03790987

Customs Code

2922509090

FAQ

What are the physical and chemical properties of 3'-Amino-2'-hydroxyacetophenone hydrochloride (CAS: 90005-55-3)?

3'-Amino-2'-hydroxyacetophenone hydrochloride is a white crystalline solid with a molecular weight of approximately 233.73 g/mol. It is soluble in water and alcohol, and is moderately reactive under basic conditions. The compound is stable under normal storage conditions but should be handled with care due to its sensitivity to strong acids.

How is 3'-Amino-2'-hydroxyacetophenone hydrochloride (CAS: 90005-55-3) typically synthesized?

3'-Amino-2'-hydroxyacetophenone hydrochloride is synthesized by reacting 3-hydroxyacetophenone with ammonia in the presence of hydrochloric acid. This process involves condensation followed by protonation, yielding the hydrochloride salt. The reaction is typically conducted under mild conditions to ensure high selectivity and yield.

What industries use 3'-Amino-2'-hydroxyacetophenone hydrochloride (CAS: 90005-55-3)?

3'-Amino-2'-hydroxyacetophenone hydrochloride finds applications in the pharmaceutical industry for the synthesis of certain drugs, and in the chemical industry for the production of intermediates. Its use is also explored in sensor technology and as a building block for polymers.

What precautions should be taken when handling 3'-Amino-2'-hydroxyacetophenone hydrochloride (CAS: 90005-55-3)?

When handling 3'-Amino-2'-hydroxyacetophenone hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to prevent inhalation. Proper spill cleanup procedures should be followed, and the material safety data sheet (MSDS) should be consulted for detailed information on storage and disposal.