3'-Amino-2'-hydroxyacetophenone hydrochloride(CAS: 90005-55-3)

3'-Amino-2'-hydroxyacetophenone hydrochloride is a white crystalline solid with a molecular weight of approximately 233.73 g/mol. It is soluble in water and alcohol, and is moderately reactive under basic conditions. The compound is stable under normal storage conditions but should be handled with care due to its sensitivity to strong acids.

3'-Amino-2'-hydroxyacetophenone hydrochloride is synthesized by reacting 3-hydroxyacetophenone with ammonia in the presence of hydrochloric acid. This process involves condensation followed by protonation, yielding the hydrochloride salt. The reaction is typically conducted under mild conditions to ensure high selectivity and yield.

3'-Amino-2'-hydroxyacetophenone hydrochloride finds applications in the pharmaceutical industry for the synthesis of certain drugs, and in the chemical industry for the production of intermediates. Its use is also explored in sensor technology and as a building block for polymers.

When handling 3'-Amino-2'-hydroxyacetophenone hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to prevent inhalation. Proper spill cleanup procedures should be followed, and the material safety data sheet (MSDS) should be consulted for detailed information on storage and disposal.