(E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid | CAS No. 899809-64-4
(E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid
Basic Information
CAS Number
899809-64-4
Molecular Formula
C9H11NO4
Molecular Weight
197.19 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
415.8°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- (E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid
- (E)-3-(5-nitrocyclohexen-1-yl)prop-2-enoic acid
- 2-Propenoic acid, 3-(5-nitro-1-cyclohexen-1-yl)-, (2E)-
- I14-8081
- (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylicacid
- (2E)-3-(5-Nitro-1-cyclohexen-1-yl)-2-propenoic acid
- 3-(5-nitrocyclohex-1-enyl)acrylic acid
- OR350479
- AX8249810
- (2E)-3-(5-nitrocyclohex-1-enyl)acrylic acid
- (2E)-3-(5-Nitrocyclohex-1-en-1-yl)prop-2-enoic acid
- (2E)-3-(5-Nitro-1-cyclohexen-1-yl)-2-propenoic acid (ACI)
- (2E)-3-(5-nitrocyclohex-1-en-1-yl)prop-2-enoic acid
- AKOS015918295
- LS-13629
- CS-0068804
- F17855
- A1-03407
- DS-5708
- AC-30216
- 899809-64-4
- DTXSID10657928
- MFCD16877199
- SCHEMBL2286986
- ZKB80964
MDL Number
MFCD16877199
FAQ
What are the physical and chemical properties of (E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid (CAS: 899809-64-4)?
(E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid is a white crystalline solid with a molecular weight of approximately 222.16 g/mol. It has a pKa of 2.8 and is slightly soluble in water. This compound is known for its reactivity, particularly in esterification and amidation reactions.
How is (E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid (CAS: 899809-64-4) typically synthesized?
This compound can be synthesized via the nitration of (E)-3-(cyclohex-1-en-1-yl)acrylic acid followed by dehydration. Commonly, nitric acid and sulfuric acid are used as the nitrating mixture under controlled conditions. The yield is generally around 70-80%, and the product is purified by recrystallization.
What industries use (E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid (CAS: 899809-64-4)?
This compound is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry, where it can be incorporated into polymers for enhancing specific properties. Additionally, it is used in the production of sensors and semiconductors due to its unique chemical structure.
What precautions should be taken when handling (E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid (CAS: 899809-64-4)?
When handling (E)-3-(5-Nitrocyclohex-1-en-1-yl)acrylic acid, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat is essential. Work should be conducted in a well-ventilated fume hood to minimize exposure to the compound. Spills should be handled carefully using appropriate absorbents, and the Material Safety Data Sheet (MSDS) should be consulted for detailed spill procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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