(2-Hydroxy-1-naphthyl)boronic acid | CAS No. 898257-48-2

(2-Hydroxy-1-naphthyl)boronic acid

Basic Information

CAS Number

898257-48-2

Molecular Formula

C10H9BO3

Molecular Weight

187.99 g/mol

AD

Basic Physical Properties

B(C1=C(C=CC2=CC=CC=C12)O)(O)O

InChI

InChI=1S/C10H9BO3/c12-9-6-5-7-3-1-2-4-8(7)10(9)11(13)14/h1-6,12-14H

InChIKey

GDVCCKPVARLVLL-UHFFFAOYSA-N

LogP

0.22519999999999973

Topological Polar Surface Area

60.69 Ų

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

198

Synonyms & References

English

  • MFCD09751353
  • 2-Naphthol-1-boronic acid
  • 898257-48-2
  • 2-Hydroxyl-1-naphthaleneboronicacid
  • FT-0695542
  • AKOS006327527
  • (2-hydroxynaphthalen-1-yl)boronic acid
  • SCHEMBL12734305
  • (2-Hydroxynaphthalen-1-yl)boronicacid
  • DTXSID00717262
  • 2-HYDROXYL-1-NAPHTHALENEBORONIC ACID

MDL Number

MFCD09751353

FAQ

What are the physical and chemical properties of (2-Hydroxy-1-naphthyl)boronic acid (CAS: 898257-48-2)?

(2-Hydroxy-1-naphthyl)boronic acid is a white to off-white crystalline solid with a molecular weight of approximately 205.21 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it exhibits moderate reactivity, particularly in reactions involving boronate ester formation or in the presence of transition metals for catalytic coupling reactions.

How is (2-Hydroxy-1-naphthyl)boronic acid (CAS: 898257-48-2) typically synthesized?

(2-Hydroxy-1-naphthyl)boronic acid can be synthesized through the reduction of 2-naphthoquinone with a suitable reducing agent such as sodium borohydride. Alternatively, it can be prepared by the reaction of 1-naphthol with boron trichloride in the presence of an appropriate base. The yield and selectivity can be optimized using specific conditions and catalysts.

What industries use (2-Hydroxy-1-naphthyl)boronic acid (CAS: 898257-48-2)?

(2-Hydroxy-1-naphthyl)boronic acid finds applications in pharmaceuticals, where it can serve as a precursor for synthesizing drug candidates. It is also used in the polymer industry for designing functional materials and in the development of sensors due to its reactivity and solubility properties. Additionally, it has potential uses in semiconductor technology for specific chemical processes.

What precautions should be taken when handling (2-Hydroxy-1-naphthyl)boronic acid (CAS: 898257-48-2)?

When handling (2-Hydroxy-1-naphthyl)boronic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation of any fumes. Spills should be cleaned up carefully, and the Safety Data Sheet (SDS) should be referenced for detailed emergency procedures.

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