5-Chloro-2-cyanopyridine

Basic Information

View in Editor

CAS Number

89809-64-3

Molecular Formula

C6H3ClN2

Molecular Weight

138.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

107.0 to 111.0 deg-C

Boiling Point

110°C/3mmHg

Density

1.33

Flash Point

98.5℃

Refractive Index

1.565

SMILES

View in Editor

C1=CC(=NC=C1Cl)C#N

InChI

InChI=1S/C6H3ClN2/c7-5-1-2-6(3-8)9-4-5/h1-2,4H

InChIKey

WTHODOKFSYPTKA-UHFFFAOYSA-N

LogP

1.60668

Complexity

137

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

5-Chloro-2-cyanopyridine
5-Chloropicolinonitrile
2-chloro-6-cyanopyridine
6-Cyano-3-chloropyridine
5-Chloro-2-pyridinecarbonitrile
5-chloropyridine-2-carbonitrile
3-Chloro-6-cyanopyridine
2-Pyridinecarbonitrile, 5-chloro-
2-Cyano-5-chloro pyridine
2-cyano-5-chloropyridine
PubChem2107
5-chloropicolinenitrile
KSC494E8L
AMPD00140
2-Pyridinecarbonitrile,5-chloro-
5-chloro-pyridine-2-carbonitrile
WTHODOKFSYPTKA-UHFFFAOYSA-N
5-chloranylpyrid
5-Chloro-2-pyridinecarbonitrile (ACI)
2-Cyano-5-chloropyridine
A843328
Q-101262
SCHEMBL69932
RB1002
BBL100618
DTXSID90397072
AKOS005255050
5-chloro-2-cyano pyridine
5-chloranylpyridine-2-carbonitrile
BCP22240
CS-W019579

MDL Number

MFCD03788835

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Chloro-2-cyanopyridine (CAS: 89809-64-3)?

5-Chloro-2-cyanopyridine (CAS: 89809-64-3) is a crystalline solid with a molecular weight of approximately 147.57 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. The compound is known for its high reactivity, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis.

How is 5-Chloro-2-cyanopyridine (CAS: 89809-64-3) typically synthesized?

5-Chloro-2-cyanopyridine (CAS: 89809-64-3) can be synthesized through the reaction of chloropyridine with acetonitrile in the presence of a suitable base like potassium carbonate. The process is known for its good yield and selectivity, making it a common method in preparative organic chemistry.

What industries use 5-Chloro-2-cyanopyridine (CAS: 89809-64-3)?

5-Chloro-2-cyanopyridine (CAS: 89809-64-3) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also utilized in the polymer industry for the development of new materials, and in the sensor and semiconductor sectors for specific applications requiring its unique properties.

What precautions should be taken when handling 5-Chloro-2-cyanopyridine (CAS: 89809-64-3)?

When handling 5-Chloro-2-cyanopyridine (CAS: 89809-64-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handling should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.