5-Chloro-2-cyanopyridine(CAS: 89809-64-3)

5-Chloro-2-cyanopyridine (CAS: 89809-64-3) is a crystalline solid with a molecular weight of approximately 147.57 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetonitrile. The compound is known for its high reactivity, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis.

5-Chloro-2-cyanopyridine (CAS: 89809-64-3) can be synthesized through the reaction of chloropyridine with acetonitrile in the presence of a suitable base like potassium carbonate. The process is known for its good yield and selectivity, making it a common method in preparative organic chemistry.

5-Chloro-2-cyanopyridine (CAS: 89809-64-3) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also utilized in the polymer industry for the development of new materials, and in the sensor and semiconductor sectors for specific applications requiring its unique properties.

When handling 5-Chloro-2-cyanopyridine (CAS: 89809-64-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handling should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.