2,3-Dichloro-4-(trifluoromethyl)pyridine

Basic Information

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CAS Number

89719-93-7

Molecular Formula

C6H2Cl2F3N

Molecular Weight

215.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CN=C(C(=C1C(F)(F)F)Cl)Cl

InChI

InChI=1S/C6H2Cl2F3N/c7-4-3(6(9,10)11)1-2-12-5(4)8/h1-2H

InChIKey

ZFCZNQZILNNPBH-UHFFFAOYSA-N

LogP

3.4072000000000005

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

161

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AM62446
LD-0253
CS-0060698
AKOS005073282
SCHEMBL364870
MFCD14525481
2,3-Dichloro-4-trifluoromethylpyridine
ZFCZNQZILNNPBH-UHFFFAOYSA-N
2,3-Dichloro-4-trifluoromethyl-pyridine
DTXSID30568744
2,3-dichloro-4-(trifluoromethyl)pyridine
89719-93-7
Pyridine, 2,3-dichloro-4-(trifluoromethyl)-
2,3-Dichloro-4-(trifluoromethyl)pyridine

MDL Number

MFCD14525481

FAQ

What are the physical and chemical properties of 2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7)?

2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7) is a crystalline solid with a molecular weight of approximately 244.02 g/mol. It is slightly soluble in water but has high solubility in organic solvents such as ethanol and acetone. Chemically, it is highly reactive and can undergo nucleophilic substitution and electrophilic aromatic substitution. It is also known for its stability under basic conditions but can react with strong acids.

How is 2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7) typically synthesized?

2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7) is commonly synthesized via a multistep process involving the reaction of 4-chloropyridine with chlorine gas, followed by trifluoromethylation using triflic anhydride. This synthesis typically yields a product with good selectivity and high yield. The reaction conditions and catalysts used can vary, but the overall process is well-documented in the literature.

What industries use 2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7)?

2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for modifying the properties of polymers, in sensor technology for developing selective gas sensors, and in the semiconductor industry for its use in etching processes. Its unique chemical properties make it a valuable reagent in these fields.

What precautions should be taken when handling 2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7)?

When handling 2,3-Dichloro-4-(trifluoromethyl)pyridine (CAS: 89719-93-7), it is essential to use proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be handled in a fume hood due to its volatility and potential to form toxic fumes. In case of a spill, it should be cleaned up according to the Material Safety Data Sheet (MSDS) guidelines. Always refer to the latest SDS for detailed safety information.