2-Methoxy-3-methyl-5-nitropyridine

Basic Information

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CAS Number

89694-10-0

Molecular Formula

C7H8N2O3

Molecular Weight

168.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

92-96°C

Boiling Point

279.7℃ at 760 mmHg

SMILES

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CC1=CC(=CN=C1OC)[N+](=O)[O-]

InChI

InChI=1S/C7H8N2O3/c1-5-3-6(9(10)11)4-8-7(5)12-2/h3-4H,1-2H3

InChIKey

HEDKXDCXKNQWEX-UHFFFAOYSA-N

LogP

1.83000

Complexity

169

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Methoxy-3-methyl-5-nitropyridine
2-Methoxy-3-methyl-5-nitropyridine
2-Methoxy-5-nitro-3-picoline
4-Iodo-2-Methylaniline
3-Picoline,2-methoxy-5-nitro- (7CI)
Pyridine, 2-methoxy-3-methyl-5-nitro-
2-methoxy-3-methyl-5-nitro-pyridine
PubChem3530
HEDKXDCXKNQWEX-UHFFFAOYSA-N
FCH849678
VP15233
AB20995
Q552
SY031480
OR345449
AX8022087
AB0017659
ST2410075
AM20061605
ST24040756
2-Methoxy-3-methyl-5-nitropyridine (ACI)
3-Picoline, 2-methoxy-5-nitro- (7CI)
GS-3107
I10117
MFCD04972416
AC-9394
DB-025173
89694-10-0
GEO-03666
J-509790
CS-0063957

MDL Number

MFCD04972416

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methoxy-3-methyl-5-nitropyridine (CAS: 89694-10-0)?

2-Methoxy-3-methyl-5-nitropyridine is a crystalline compound with a molecular weight of approximately 203.13 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol, methanol, and acetone. The compound is moderately reactive, particularly towards reducing agents and bases. It decomposes above 250°C and shows good thermal stability below this temperature.

How is 2-Methoxy-3-methyl-5-nitropyridine (CAS: 89694-10-0) typically synthesized?

2-Methoxy-3-methyl-5-nitropyridine can be synthesized through a series of steps including nitration of 2-methoxy-3-methylpyridine followed by reduction of the nitro group. Common catalysts used include sulfuric acid and metallic palladium. The overall yield is around 70-80%, with high selectivity for the desired product.

What industries use 2-Methoxy-3-methyl-5-nitropyridine (CAS: 89694-10-0)?

2-Methoxy-3-methyl-5-nitropyridine is primarily used in the pharmaceutical and agrochemical industries for the synthesis of various active pharmaceutical ingredients (APIs) and herbicides. It is also used in the polymer industry for the development of advanced materials and in the electronics sector for sensor applications and semiconductor processing.

What precautions should be taken when handling 2-Methoxy-3-methyl-5-nitropyridine (CAS: 89694-10-0)?

When handling 2-Methoxy-3-methyl-5-nitropyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal guidelines.