2-Methoxy-3-methyl-5-nitropyridine(CAS: 89694-10-0)

2-Methoxy-3-methyl-5-nitropyridine is a crystalline compound with a molecular weight of approximately 203.13 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol, methanol, and acetone. The compound is moderately reactive, particularly towards reducing agents and bases. It decomposes above 250°C and shows good thermal stability below this temperature.

2-Methoxy-3-methyl-5-nitropyridine can be synthesized through a series of steps including nitration of 2-methoxy-3-methylpyridine followed by reduction of the nitro group. Common catalysts used include sulfuric acid and metallic palladium. The overall yield is around 70-80%, with high selectivity for the desired product.

2-Methoxy-3-methyl-5-nitropyridine is primarily used in the pharmaceutical and agrochemical industries for the synthesis of various active pharmaceutical ingredients (APIs) and herbicides. It is also used in the polymer industry for the development of advanced materials and in the electronics sector for sensor applications and semiconductor processing.

When handling 2-Methoxy-3-methyl-5-nitropyridine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal guidelines.