3-Chloro-6-methoxy-4-methylpyridazine | CAS No. 89466-36-4

3-Chloro-6-methoxy-4-methylpyridazine

Basic Information

CAS Number

89466-36-4

Molecular Formula

C6H7ClN2O

Molecular Weight

158.59 g/mol

AD

Basic Physical Properties

CC1=CC(=NN=C1Cl)OC

InChI

InChI=1S/C6H7ClN2O/c1-4-3-5(10-2)8-9-6(4)7/h3H,1-2H3

InChIKey

KKUVFQSMYKCFAB-UHFFFAOYSA-N

LogP

1.4470199999999998

Topological Polar Surface Area

35.010000000000005 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

112

Synonyms & References

English

  • 3-Chloro-6-methoxy-4-methylpyridazine
  • 3-Chloro-6-methoxy-4-methylpyridazine (ACI)
  • 3-Methoxy-5-methyl-6-chloropyridazine
  • Pyridazine, 3-chloro-6-methoxy-4-methyl-
  • 89466-36-4
  • AKOS022178316
  • EN300-6209452
  • DB-151787
  • KKUVFQSMYKCFAB-UHFFFAOYSA-N
  • CS-0212370
  • SCHEMBL4097986

MDL Number

MFCD00234198

FAQ

What are the physical and chemical properties of 3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4)?

3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) is a crystalline solid with a molecular weight of approximately 195.6 g/mol. It has a low solubility in water (0.05 g/100 mL at 20°C) but is more soluble in organic solvents like ethanol and dichloromethane. This compound is moderately reactive, showing sensitivity to strong acids and bases. It is stable under normal storage conditions but should be kept away from moisture and strong oxidizers.

How is 3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) typically synthesized?

3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) is typically synthesized via the reaction of 4-methyl-6-methoxypyridazine with thionyl chloride in the presence of a base. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. Commonly, the base used is triethylamine, and the product is isolated by recrystallization or column chromatography.

What industries use 3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4)?

3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) is utilized in the pharmaceutical industry for the synthesis of certain medications. It is also employed in the polymer industry for the production of advanced materials and in the sensor industry for developing chemical sensors. Additionally, it has applications in the semiconductor industry for etching processes.

What precautions should be taken when handling 3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4)?

When handling 3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4), it is essential to use appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be performed under a fume hood to minimize exposure to vapor. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.

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