3-Chloro-6-methoxy-4-methylpyridazine(CAS: 89466-36-4)

3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) is a crystalline solid with a molecular weight of approximately 195.6 g/mol. It has a low solubility in water (0.05 g/100 mL at 20°C) but is more soluble in organic solvents like ethanol and dichloromethane. This compound is moderately reactive, showing sensitivity to strong acids and bases. It is stable under normal storage conditions but should be kept away from moisture and strong oxidizers.

3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) is typically synthesized via the reaction of 4-methyl-6-methoxypyridazine with thionyl chloride in the presence of a base. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. Commonly, the base used is triethylamine, and the product is isolated by recrystallization or column chromatography.

3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4) is utilized in the pharmaceutical industry for the synthesis of certain medications. It is also employed in the polymer industry for the production of advanced materials and in the sensor industry for developing chemical sensors. Additionally, it has applications in the semiconductor industry for etching processes.

When handling 3-Chloro-6-methoxy-4-methylpyridazine (CAS: 89466-36-4), it is essential to use appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be performed under a fume hood to minimize exposure to vapor. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.