3-Chloro-5-ethoxypyridazine

Basic Information

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CAS Number

89466-35-3

Molecular Formula

C6H7ClN2O

Molecular Weight

158.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CCOC1=CC(=NN=C1)Cl

InChI

InChI=1S/C6H7ClN2O/c1-2-10-5-3-6(7)9-8-4-5/h3-4H,2H2,1H3

InChIKey

XVEYZNWQMUVCHG-UHFFFAOYSA-N

LogP

1.5286999999999997

Topological Polar Surface Area

35.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

102

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-Aethoxy-6-chlorpyridazin
AMY36389
DTXSID90744789
AKOS016844525
DS-6959
A916680
89466-35-3
J-512265
C77015
3-chloro-5-ethoxypyridazine
CS-0186805
3-Chloro-5-ethoxypyridazine
Pyridazine, 3-chloro-5-ethoxy-
FCH1192777
AK131932
AX8252855

MDL Number

MFCD19688827

FAQ

What are the physical and chemical properties of 3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3)?

3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3) is a crystalline solid with a molecular weight of approximately 191.66 g/mol. It is slightly soluble in water but has good solubility in organic solvents like ethanol and acetone. The compound shows moderate reactivity, particularly towards nucleophiles, and is stable under normal storage conditions.

How is 3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3) typically synthesized?

3-Chloro-5-ethoxypyridazine can be synthesized through a multi-step process, typically involving the reaction of chloropyridine and ethanol in the presence of a suitable catalyst, such as a Lewis acid or a strong base. The reaction yields a mixture that is purified by recrystallization to obtain the desired compound with high selectivity and yield.

What industries use 3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3)?

3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3) is primarily used in the pharmaceutical and chemical industries. It serves as an intermediate in the synthesis of various pharmaceuticals and is also explored for its potential applications in sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3)?

When handling 3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) for disposal instructions. Ensure good ventilation and avoid contact with skin and eyes.