3-Chloro-5-ethoxypyridazine(CAS: 89466-35-3)

3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3) is a crystalline solid with a molecular weight of approximately 191.66 g/mol. It is slightly soluble in water but has good solubility in organic solvents like ethanol and acetone. The compound shows moderate reactivity, particularly towards nucleophiles, and is stable under normal storage conditions.

3-Chloro-5-ethoxypyridazine can be synthesized through a multi-step process, typically involving the reaction of chloropyridine and ethanol in the presence of a suitable catalyst, such as a Lewis acid or a strong base. The reaction yields a mixture that is purified by recrystallization to obtain the desired compound with high selectivity and yield.

3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3) is primarily used in the pharmaceutical and chemical industries. It serves as an intermediate in the synthesis of various pharmaceuticals and is also explored for its potential applications in sensors and semiconductors due to its unique chemical properties.

When handling 3-Chloro-5-ethoxypyridazine (CAS: 89466-35-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) for disposal instructions. Ensure good ventilation and avoid contact with skin and eyes.