6-Bromo-2-methoxypyridin-3-amine

Basic Information

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CAS Number

89466-18-2

Molecular Formula

C6H7BrN2O

Molecular Weight

203.04 g/mol

Basic Physical Properties

SMILES

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COC1=C(C=CC(=N1)Br)N

InChI

InChI=1S/C6H7BrN2O/c1-10-6-4(8)2-3-5(7)9-6/h2-3H,8H2,1H3

InChIKey

HSVYYOLSYNEVSP-UHFFFAOYSA-N

LogP

1.4348999999999998

Topological Polar Surface Area

48.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

112

Synonyms & References

English

3-Amino-6-bromo-2-methoxypyridine
6-Bromo-2-methoxypyridin-3-ylamine
6-Bromo-2-methoxypyridin-3-amine
3-Amino-5-bromo-2-methoxypyridine
6-Bromo-2-methoxy-3-aminopyridine
6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE
3-amino-6-bromo-2-methoxy-pyridine
5-amino-2-bromo-6-methoxypyridine
6-Bromo-2-methoxypyridine-3-amine powder
WT587
3-amino-2-methoxy-6-bromopyridine
3-Pyridinamine, 6-bromo-2-methoxy-
6-Bromo-2-methoxy-pyridin-3-yl-amine
PubChem21956
HSVYYOLSYNEVSP-UHFFFAOYSA-N
6-Bromo-2-methoxy-3-pyridinamine
6-Bromo-2-methoxypyridine-3-amine
2-Methoxy-6-bromopyridine-3-amine
3-Pyridinamine,6-bromo-2
6-Bromo-2-methoxy-3-pyridinamine (ACI)
Pyridine, 3-amino-6-bromo-2-methoxy- (7CI)
(6-Bromo-2-methoxypyridin-3-yl)amine
5-Amino-2-bromo-6-methoxypyridine
6-bromo-2-methoxypyridin-3-amine
DB-082227
DTXSID60441399
6-bromo-2-methoxypyridin-3-ylamine
MFCD06738312
EN300-107295
SB39681
89466-18-2

MDL Number

MFCD06738312

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Bromo-2-methoxypyridin-3-amine (CAS: 89466-18-2)?

6-Bromo-2-methoxypyridin-3-amine is a crystalline solid with a molecular weight of approximately 227.03 g/mol. It has a solubility of about 2.1 mg/mL in water. The compound is moderately reactive, particularly with nucleophiles. It is stable under normal storage conditions but should be stored in a cool, dry place away from moisture and heat sources.

How is 6-Bromo-2-methoxypyridin-3-amine (CAS: 89466-18-2) typically synthesized?

6-Bromo-2-methoxypyridin-3-amine is commonly synthesized via a multi-step process involving bromination of 2-methoxypyridin-3-amine followed by quenching with a base. The reaction typically proceeds with high selectivity and yields up to 90% of the desired product. Commonly used catalysts include metal halides and bases such as potassium carbonate.

What industries use 6-Bromo-2-methoxypyridin-3-amine (CAS: 89466-18-2)?

6-Bromo-2-methoxypyridin-3-amine is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in the polymer industry for developing advanced materials, as well as in the sensor industry for its functional properties. Additionally, it is utilized in semiconductor research for its electronic properties.

What precautions should be taken when handling 6-Bromo-2-methoxypyridin-3-amine (CAS: 89466-18-2)?

When handling 6-Bromo-2-methoxypyridin-3-amine, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The material should be stored in a fume hood to minimize inhalation risks. In case of a spill, it is advised to use absorbent material and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.