6-Bromo-2-methoxypyridin-3-amine(CAS: 89466-18-2)

6-Bromo-2-methoxypyridin-3-amine is a crystalline solid with a molecular weight of approximately 227.03 g/mol. It has a solubility of about 2.1 mg/mL in water. The compound is moderately reactive, particularly with nucleophiles. It is stable under normal storage conditions but should be stored in a cool, dry place away from moisture and heat sources.

6-Bromo-2-methoxypyridin-3-amine is commonly synthesized via a multi-step process involving bromination of 2-methoxypyridin-3-amine followed by quenching with a base. The reaction typically proceeds with high selectivity and yields up to 90% of the desired product. Commonly used catalysts include metal halides and bases such as potassium carbonate.

6-Bromo-2-methoxypyridin-3-amine is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in the polymer industry for developing advanced materials, as well as in the sensor industry for its functional properties. Additionally, it is utilized in semiconductor research for its electronic properties.

When handling 6-Bromo-2-methoxypyridin-3-amine, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The material should be stored in a fume hood to minimize inhalation risks. In case of a spill, it is advised to use absorbent material and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.