Dimethyloxalylglycine

Basic Information

View in Editor

CAS Number

89464-63-1

Molecular Formula

C6H9NO5

Molecular Weight

175.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

49.0 to 53.0 deg-C

Boiling Point

182°C/12mmHg

Density

1.246±0.06 g/cm3 (20 ºC 760 Torr),

Water Solubility

Soluble in water at 30mg/ml.

SMILES

View in Editor

COC(=O)CNC(=O)C(=O)OC

InChI

InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)

InChIKey

BNJOZDZCRHCODO-UHFFFAOYSA-N

LogP

-1.551399999999999

Topological Polar Surface Area

81.69999999999999 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

200

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Glycine,N-(2-methoxy-2-oxoacetyl)-, methyl ester
Dimethyloxaloylglycine
DMOG
Dimethyloxallyl Glycine
Dimethyloxaloylglycine (DMOG)
Dimethyloxalylglycine
methyl 2-[(2-methoxy-2-oxoethyl)amino]-2-oxoacetate
N-(2-methoxy-2-oxoacetyl)Glycine methyl ester
N-(Methoxyoxoacetyl)-glycine methyl ester
N-[Methoxy(oxo)acetyl]glycine Methyl Ester
N-[(Methoxycarbonyl)methyl]oxamic acid methyl ester
methyl 2-((2-methoxy-2-oxoethyl)amino)-2-oxoacetate
BNJOZDZCRHCODO-UHFFFAOYSA-N
Glycine, N-(methoxyoxoacetyl)-, methyl ester
METHYL 2-(2-METHOXY-2-OXOETHYLAMINO)-2-OXOACETATE
methyl n-[methoxy(oxo)acetyl]glycinate
dimethyl oxalylglycine
methyl 2-(2-methoxy-2-oxoacetamido)acetate
Dimethy
Glycine, N-(methoxyoxoacetyl)-, methyl ester (9CI)
Oxamic acid, (carboxymethyl)-, dimethyl ester (7CI)
2: PN: US6833489 FIGURE: 1 claimed protein
Dimethyloxallyl glycine
CHEBI:102218
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
methyl[(2-methoxy-2-oxoethyl)amino](oxo)acetate
AB22926
EN300-141546
DTXSID80339961
DIMETHYLOXALOYLGLYCINE
89464-63-1

MDL Number

MFCD05865098

Customs Code

2924199090

FAQ

What are the physical and chemical properties of Dimethyloxalylglycine (CAS: 89464-63-1)?

Dimethyloxalylglycine (DMOG) is a white crystalline solid with a molecular weight of approximately 168.13 g/mol. It has a pKa value of around 2.5, making it slightly acidic. DMOG is poorly soluble in water but soluble in organic solvents like methanol and ethanol. It reacts readily with bases and exhibits reduced reactivity with acids. DMOG is stable under normal conditions but may degrade over time in acidic environments.

How is Dimethyloxalylglycine (CAS: 89464-63-1) typically synthesized?

Dimethyloxalylglycine (DMOG) is often synthesized by the reaction of oxaloacetic acid with dimethylamine. The reaction typically requires a base catalyst such as sodium hydroxide, and the product is isolated by crystallization. The yield of DMOG is around 70-80%, and the synthesis is highly selective. This method allows for the production of DMOG in a relatively straightforward manner with good purity.

What industries use Dimethyloxalylglycine (CAS: 89464-63-1)?

Dimethyloxalylglycine (DMOG) is used in various industries. In pharmaceuticals, it serves as a metabolic intermediate and a research tool. It is also utilized in polymer production, where it can act as a crosslinking agent. Additionally, DMOG is employed in sensor technology for detecting specific compounds. It has applications in semiconductor processing for its reactivity with certain materials. DMOG's versatility makes it a valuable reagent in multiple fields.

What precautions should be taken when handling Dimethyloxalylglycine (CAS: 89464-63-1)?

When handling Dimethyloxalylglycine (DMOG), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or under a fume hood to minimize inhalation. Spills should be cleaned up using appropriate absorbent materials and the area should be thoroughly rinsed. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage. DMOG should be stored in a cool, dry place away from strong acids and bases to prevent degradation.