Dimethyloxalylglycine(CAS: 89464-63-1)

Dimethyloxalylglycine (DMOG) is a white crystalline solid with a molecular weight of approximately 168.13 g/mol. It has a pKa value of around 2.5, making it slightly acidic. DMOG is poorly soluble in water but soluble in organic solvents like methanol and ethanol. It reacts readily with bases and exhibits reduced reactivity with acids. DMOG is stable under normal conditions but may degrade over time in acidic environments.

Dimethyloxalylglycine (DMOG) is often synthesized by the reaction of oxaloacetic acid with dimethylamine. The reaction typically requires a base catalyst such as sodium hydroxide, and the product is isolated by crystallization. The yield of DMOG is around 70-80%, and the synthesis is highly selective. This method allows for the production of DMOG in a relatively straightforward manner with good purity.

Dimethyloxalylglycine (DMOG) is used in various industries. In pharmaceuticals, it serves as a metabolic intermediate and a research tool. It is also utilized in polymer production, where it can act as a crosslinking agent. Additionally, DMOG is employed in sensor technology for detecting specific compounds. It has applications in semiconductor processing for its reactivity with certain materials. DMOG's versatility makes it a valuable reagent in multiple fields.

When handling Dimethyloxalylglycine (DMOG), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or under a fume hood to minimize inhalation. Spills should be cleaned up using appropriate absorbent materials and the area should be thoroughly rinsed. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage. DMOG should be stored in a cool, dry place away from strong acids and bases to prevent degradation.