5-bromo-3-piperazin-1-yl-pyrazin-2-amine

Basic Information

View in Editor

CAS Number

893611-67-1

Molecular Formula

C8H12BrN5

Molecular Weight

258.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

428.5°C at 760 mmHg

SMILES

View in Editor

C1CN(CCN1)C2=NC(=CN=C2N)Br

InChI

InChI=1S/C8H12BrN5/c9-6-5-12-7(10)8(13-6)14-3-1-11-2-4-14/h5,11H,1-4H2,(H2,10,12)

InChIKey

UMJBQCDGKLHYPT-UHFFFAOYSA-N

LogP

0.23089999999999994

Topological Polar Surface Area

67.07 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

185

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6'-Bromo-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-3'-ylamine
C8H12BrN5
2-Amino-5-bromo-3-piperazin-1-ylpyrazine
AKOS005257136
DTXSID80587501
AS-30575
893611-67-1
A861230
2-Pyrazinamine,5-bromo-3-(1-piperazinyl)-
MFCD08056162
5-bromo-3-piperazin-1-ylpyrazin-2-amine
FT-0646674
5-bromo-3-(piperazin-1-yl)pyrazin-2-amine
5-Bromo-3-(piperazin-1-yl)pyrazin-2-amine
6'-BROMO-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL-3'-YLAMINE
SBB101968
FCH1386158
5-bromo-3-piperazinylpyrazine-2-ylamine
EN000835
AX8070348
AB0027397
ST2418654
W9226

MDL Number

MFCD08056162

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 5-bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1)?

5-Bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1) is a crystalline solid with a molecular weight of approximately 323.04 g/mol. It is slightly soluble in water and has good solubility in common organic solvents like DMSO. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions. It has a high melting point and is stable under normal conditions.

How is 5-bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1) typically synthesized?

5-Bromo-3-piperazin-1-yl-pyrazin-2-amine is typically synthesized through a multi-step process involving the bromination of 3-piperazin-1-yl-pyrazin-2-amine. Commonly used reagents include N-bromosuccinimide (NBS) or bromine in the presence of an appropriate base. The synthesis involves protecting groups and requires careful control of reaction conditions to achieve high yields and selectivity.

What industries use 5-bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1)?

5-Bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1) is primarily used in the pharmaceutical and research industries. It serves as a precursor in the synthesis of various bioactive compounds, including potential therapeutic agents. Additionally, it finds applications in the development of sensors and materials science due to its unique chemical properties.

What precautions should be taken when handling 5-bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1)?

When handling 5-bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately, and the area should be thoroughly washed down with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.