5-bromo-3-piperazin-1-yl-pyrazin-2-amine(CAS: 893611-67-1)

5-Bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1) is a crystalline solid with a molecular weight of approximately 323.04 g/mol. It is slightly soluble in water and has good solubility in common organic solvents like DMSO. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions. It has a high melting point and is stable under normal conditions.

5-Bromo-3-piperazin-1-yl-pyrazin-2-amine is typically synthesized through a multi-step process involving the bromination of 3-piperazin-1-yl-pyrazin-2-amine. Commonly used reagents include N-bromosuccinimide (NBS) or bromine in the presence of an appropriate base. The synthesis involves protecting groups and requires careful control of reaction conditions to achieve high yields and selectivity.

5-Bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1) is primarily used in the pharmaceutical and research industries. It serves as a precursor in the synthesis of various bioactive compounds, including potential therapeutic agents. Additionally, it finds applications in the development of sensors and materials science due to its unique chemical properties.

When handling 5-bromo-3-piperazin-1-yl-pyrazin-2-amine (CAS: 893611-67-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately, and the area should be thoroughly washed down with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.