4-Chloro-3-cyanopyridine

Basic Information

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CAS Number

89284-61-7

Molecular Formula

C6H3ClN2

Molecular Weight

127.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

SMILES

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C1=CN=CC(=C1Cl)C#N

InChI

InChI=1S/C6H3ClN2/c7-6-1-2-9-4-5(6)3-8/h1-2,4H

InChIKey

QBKPXDUZFDINDV-UHFFFAOYSA-N

LogP

2.04342

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

137

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H331 Toxic if inhaled
Acute toxicity, inhalation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

4-Chloronicotinonitrile
4-CHLORO-3-CYANOPYRIDINE
4-Chloro-3-pyridinecarbonitrile
4-chloropyridine-3-carbonitrile
4-chloro-nicotinonitrile
3-Pyridinecarbonitrile, 4-chloro-
3-Pyridinecarbonitrile,4-chloro-
KSC662O9F
QBKPXDUZFDINDV-UHFFFAOYSA-N
BCP22072
RW3678
BBL103187
STL556997
RW2860
VP14688
AB43637
ST2411366
AB0007690
4-Chloro-3-pyridinecarbonitrile (ACI)
Nicotinonitrile, 4-chloro- (7CI)
4-Chloro-3-cyanopyridine
4-Chloropyridine-3-carbonitrile
SY109553
Z1198176516
MFCD08234759
GS-6690
89284-61-7
4-CHLORO-3-PYRIDINECARBONITRILE
J-514998
CS-W018972
AC-23017

MDL Number

MFCD08234759

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Chloro-3-cyanopyridine (CAS: 89284-61-7)?

4-Chloro-3-cyanopyridine is a crystalline solid with a molecular weight of approximately 169.57 g/mol. It has a solubility of around 100 mg/L in water and is sparingly soluble in ethanol and acetone. Chemically, it is moderately reactive, showing electrophilic aromatic substitution and nucleophilic addition properties.

How is 4-Chloro-3-cyanopyridine (CAS: 89284-61-7) typically synthesized?

4-Chloro-3-cyanopyridine is typically synthesized via the cyanation of 4-chloropyridine. This process involves the use of copper iodide as a catalyst, providing good yield and selectivity. The reaction is usually carried out in an inert atmosphere and at controlled temperatures to ensure optimal reaction conditions.

What industries use 4-Chloro-3-cyanopyridine (CAS: 89284-61-7)?

4-Chloro-3-cyanopyridine is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the production of special plastics and in the semiconductor industry for photoresists. Additionally, it finds applications in the development of sensors and as a precursor for other chemical compounds.

What precautions should be taken when handling 4-Chloro-3-cyanopyridine (CAS: 89284-61-7)?

When handling 4-Chloro-3-cyanopyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The substance should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.