5-Cyclopropyl-1,3,4-oxadiazol-2-amine

Basic Information

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CAS Number

89179-60-2

Molecular Formula

C5H7N3O

Molecular Weight

125.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

282 ºC

Density

1.406

Flash Point

124 ºC

Refractive Index

1.614

SMILES

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C1CC1C2=NN=C(O2)N

InChI

InChI=1S/C5H7N3O/c6-5-8-7-4(9-5)3-1-2-3/h3H,1-2H2,(H2,6,8)

InChIKey

BXHGGEZILMHEAM-UHFFFAOYSA-N

LogP

0.5291999999999998

Topological Polar Surface Area

64.94 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

115

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

5-Cyclopropyl-1,3,4-oxadiazol-2-amine
1,3,4-Oxadiazol-2-amine,5-cyclopropyl-
1,3,4-Oxadiazol-2-amine,5-cyclopropyl
5-Amino-2-cyclopropyl-1,3,4-oxadiazol
5-cyclopropyl-1,3,4-oxadiazol-2-amine(SALTDATA: FREE)
F2182-0120
5-cyclopropyl-1,3,4-oxadiazol-2-amine
1,3,4-Oxadiazole, 2-amino-5-cyclopropyl- (7CI)
5-Cyclopropyl-1,3,4-oxadiazol-2-amine (ACI)
(5-Cyclopropyl-1,3,4-oxadiazol-2-yl)amine
DTXSID00588015
MFCD09041179
BXHGGEZILMHEAM-UHFFFAOYSA-N
Z235362809
DA-18455
1,3,4-OXADIAZOL-2-AMINE, 5-CYCLOPROPYL-
2-Amino-5-cyclopropyl-1,3,4-oxadiazol
ALBB-010697
EN300-29742
5-Cyclopropyl-1,3,4-oxadiazol-2-amine, AldrichCPR
BS-13007
SCHEMBL1924555
89179-60-2
AKOS000123461
CS-W011175
2-Amino-5-cyclopropyl-1,3,4-oxadiazole
P10685
SY083051
5-Cyclopropyl-[1,3,4]oxadiazol-2-ylamine
PB34357

MDL Number

MFCD09041179

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2)?

5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2) is a crystalline solid with a molecular weight of approximately 161.19 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and acetonitrile. This compound is known for its reactivity, particularly towards nucleophiles and reducing agents. It can undergo ring-opening reactions and electrophilic substitution reactions.

How is 5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2) typically synthesized?

5-Cyclopropyl-1,3,4-oxadiazol-2-amine can be synthesized by reacting cyclopropylacetonitrile with dioxamide in the presence of a base like sodium hydride. The reaction typically gives high yields and good selectivity, with the product being purified by recrystallization from an appropriate solvent.

What industries use 5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2)?

5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2) is used in the pharmaceutical industry for its potential as a drug candidate. It is also utilized in the polymer industry for its reactive functionality. Additionally, it can be used in the development of sensors and as a precursor in the semiconductor industry for its electronic properties.

What precautions should be taken when handling 5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2)?

When handling 5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. The substance should be handled in a well-ventilated area or fume hood. In case of a spill, it should be contained and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.