5-Cyclopropyl-1,3,4-oxadiazol-2-amine(CAS: 89179-60-2)

5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2) is a crystalline solid with a molecular weight of approximately 161.19 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and acetonitrile. This compound is known for its reactivity, particularly towards nucleophiles and reducing agents. It can undergo ring-opening reactions and electrophilic substitution reactions.

5-Cyclopropyl-1,3,4-oxadiazol-2-amine can be synthesized by reacting cyclopropylacetonitrile with dioxamide in the presence of a base like sodium hydride. The reaction typically gives high yields and good selectivity, with the product being purified by recrystallization from an appropriate solvent.

5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2) is used in the pharmaceutical industry for its potential as a drug candidate. It is also utilized in the polymer industry for its reactive functionality. Additionally, it can be used in the development of sensors and as a precursor in the semiconductor industry for its electronic properties.

When handling 5-Cyclopropyl-1,3,4-oxadiazol-2-amine (CAS: 89179-60-2), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. The substance should be handled in a well-ventilated area or fume hood. In case of a spill, it should be contained and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.